# Metastasis

Source: https://onco.cc/key-papers/paper-gerstberger-cell/  
OnCo record `paper-gerstberger-cell` (Key paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Paper cited by one pathway page, indexed on Europe PMC as PubMed record 37059065 and published in Cell; the citing page links this DOI, which is how the record was matched.

## Summary

Most cancer-associated deaths occur due to metastasis, yet our understanding of metastasis as an evolving, heterogeneous, systemic disease and of how to effectively treat it is still emerging. Metastasis requires the acquisition of a succession of traits to disseminate, variably enter and exit dormancy, and colonize distant organs. The success of these events is driven by clonal selection, the potential of metastatic cells to dynamically transition into distinct states, and their ability to co-opt the immune environment. Here, we review the main principles of metastasis and highlight emerging opportunities to develop more effective therapies for metastatic cancer.

Indexed on Europe PMC as PubMed record 37059065 (DOI 10.1016/j.cell.2023.03.003). Matched by DOI alone: one pathway page cites this DOI among its external links (the pages are listed under Related), and this page was written so that the citation resolves inside OnCo. No figure has been checked by an editor.

## Fields

- Kind: Key paper
- Last checked: 2026-09-22
- Tags: europepmc-ingest
- Journal: Cell
- Year: 2023
- DOI: 10.1016/j.cell.2023.03.003
- Authors: Gerstberger S, Jiang Q, Ganesh K
- What it means: One pathway page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
- Caveats: Matched to the citing OnCo records by DOI alone; the summary reproduces the Europe PMC abstract and no figure has been verified against the full paper.

## Sources

- Cell 2023: https://doi.org/10.1016/j.cell.2023.03.003
- PubMed: https://pubmed.ncbi.nlm.nih.gov/37059065/
- Europe PMC: https://europepmc.org/article/MED/37059065

## Connected records

- pathways: [The metastatic cascade](https://onco.cc/pathways/metastatic-cascade/)
- journals: [Cell](https://onco.cc/journals/cell/)

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