# Recommendations for a more organized and effective approach to the early detection of pancreatic cancer from the PRECEDE (Pancreatic Cancer Early Detection) consortium

Source: https://onco.cc/key-papers/paper-gonda-precede-consortium-recommendations-gastroenterology-2021/  
OnCo record `paper-gonda-precede-consortium-recommendations-gastroenterology-2021` (Key paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The PRECEDE consortium set out how the field should organise itself to detect pancreatic cancer early: shared enrolment criteria, a common data and biospecimen registry, and international collaboration rather than isolated single-centre cohorts.

## Summary

The Pancreatic Cancer Early Detection consortium published recommendations for a more organised and effective approach to early detection of pancreatic cancer, covering the coordination of high-risk cohorts, standardised data collection and biospecimen banking across centres.

## Fields

- Kind: Key paper
- Last checked: 2026-09-24
- Journal: Gastroenterology
- Year: 2021
- DOI: 10.1053/j.gastro.2021.08.036
- Authors: Gonda TA, Everett JN, Wallace M, Simeone DM, PRECEDE Consortium.
- Findings: A coordinated multi-centre structure for high-risk cohorts, data and biospecimens is proposed.
- What it means: PRECEDE is the infrastructure answer to CAPS's problem: no single centre can enrol enough high-risk people to validate an early detection test.
- Caveats: Recommendations, not results; no abstract text is indexed for this record.; Outcomes from the consortium cohort are not yet published.

## Sources

- Gonda et al., Gastroenterology 2021: PRECEDE consortium recommendations for early detection: https://doi.org/10.1053/j.gastro.2021.08.036
- PubMed: https://pubmed.ncbi.nlm.nih.gov/34454916/

## Connected records

- cancers: [Pancreatic ductal adenocarcinoma](https://onco.cc/cancers/pancreatic/)
- technologies: [High-risk pancreatic surveillance (CAPS / PRECEDE)](https://onco.cc/technologies/pancreatic-surveillance/), [Liquid biopsy (ctDNA)](https://onco.cc/technologies/liquid-biopsy/)
- institutions: [Laura and Isaac Perlmutter Cancer Center at NYU Langone Health](https://onco.cc/institutions/nyu-perlmutter/)
- trials: [PRECEDE](https://onco.cc/trials/precede/)
- people: [Diane M. Simeone](https://onco.cc/people/diane-simeone/)
- journals: [Gastroenterology](https://onco.cc/journals/gastroenterology/)

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