# Cancer-susceptibility genes. Gatekeepers and caretakers

Source: https://onco.cc/key-papers/paper-kinzler-nature/  
OnCo record `paper-kinzler-nature` (Key paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Paper cited by one pathway page and one term page, indexed on Europe PMC as PubMed record 9126728 and published in Nature; the citing pages link this DOI, which is how the record was matched.

## Summary

Europe PMC indexes no abstract for this record; the title is the only text available.

Indexed on Europe PMC as PubMed record 9126728 (DOI 10.1038/386761a0). Matched by DOI alone: one pathway page and one term page cite this DOI among their external links (the pages are listed under Related), and this page was written so that the citation resolves inside OnCo. No figure has been checked by an editor.

## Fields

- Kind: Key paper
- Last checked: 2026-09-22
- Tags: europepmc-ingest
- Journal: Nature
- Year: 1997
- DOI: 10.1038/386761a0
- Authors: Kinzler KW, Vogelstein B
- What it means: One pathway page and one term page on OnCo cite this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing pages listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
- Caveats: Matched to the citing OnCo records by DOI alone; the summary reproduces the Europe PMC abstract and no figure has been verified against the full paper.

## Sources

- Nature 1997: https://doi.org/10.1038/386761a0
- PubMed: https://pubmed.ncbi.nlm.nih.gov/9126728/
- Europe PMC: https://europepmc.org/article/MED/9126728

## Connected records

- pathways: [Drivers, passengers & the two-hit model](https://onco.cc/pathways/oncogene-activation-two-hit/)
- terms: [Driver and passenger mutations: the refined somatic mutation theory](https://onco.cc/terms/driver-passenger-model/)
- journals: [Nature](https://onco.cc/journals/nature/)

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