# What are the hallmarks of cancer?

Source: https://onco.cc/key-papers/paper-lazebnik-nat-rev-cancer/  
OnCo record `paper-lazebnik-nat-rev-cancer` (Key paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Paper cited by one term page, indexed on Europe PMC as PubMed record 20355252 and published in Nature Reviews Cancer; the citing page links this DOI, which is how the record was matched.

## Summary

The seminal article by Douglas Hanahan and Robert Weinberg on the hallmarks of cancer is 10 years old this year and its contribution to how we see cancer has been substantial. But, in embracing this view, have we lost sight of what makes cancer cancer?

Indexed on Europe PMC as PubMed record 20355252 (DOI 10.1038/nrc2827). Matched by DOI alone: one term page cites this DOI among its external links (the pages are listed under Related), and this page was written so that the citation resolves inside OnCo. No figure has been checked by an editor.

## Fields

- Kind: Key paper
- Last checked: 2026-09-22
- Tags: europepmc-ingest
- Journal: Nature Reviews Cancer
- Year: 2010
- DOI: 10.1038/nrc2827
- Authors: Lazebnik Y
- What it means: One term page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
- Caveats: Matched to the citing OnCo records by DOI alone; the summary reproduces the Europe PMC abstract and no figure has been verified against the full paper.

## Sources

- Nat Rev Cancer 2010: https://doi.org/10.1038/nrc2827
- PubMed: https://pubmed.ncbi.nlm.nih.gov/20355252/
- Europe PMC: https://europepmc.org/article/MED/20355252

## Connected records

- terms: [Hallmarks of cancer as a synthesis of the theories](https://onco.cc/terms/hallmarks-synthesis/)
- journals: [Nature Reviews Cancer](https://onco.cc/journals/nature-reviews-cancer/)

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