# Revisions to the staging and classification of mycosis fungoides and Sezary syndrome (ISCL/EORTC)

Source: https://onco.cc/key-papers/paper-olsen-mycosis-fungoides-staging-blood-2007/  
OnCo record `paper-olsen-mycosis-fungoides-staging-blood-2007` (Key paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The 2007 international revision of the TNMB staging system for mycosis fungoides and Sezary syndrome defined skin, node, visceral and blood classes that remain the basis for staging, treatment choice and trial eligibility.

## Summary

Consensus proposal from the International Society for Cutaneous Lymphomas and the EORTC cutaneous lymphoma task force revising the tumour, node, metastasis and blood (TNMB) classification, defining blood involvement classes B0 to B2, patch/plaque/tumour skin classes and clinical stages IA to IVB.

## Fields

- Kind: Key paper
- Last checked: 2026-09-17
- Journal: Blood
- Year: 2007
- DOI: 10.1182/blood-2007-03-055749
- Authors: Olsen E, Vonderheid E, Pimpinelli N, et al.
- What it means: The stages quoted on the cutaneous T-cell lymphoma page and the skin-directed versus systemic treatment split by stage follow this classification.
- Caveats: Updated in 2022 to refine blood staging using flow cytometry.

## Sources

- Blood 2007: https://doi.org/10.1182/blood-2007-03-055749
- PubMed: https://pubmed.ncbi.nlm.nih.gov/17540844/

## Connected records

- cancers: [Cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)](https://onco.cc/cancers/cutaneous-t-cell-lymphoma/)
- journals: [Blood](https://onco.cc/journals/blood/)

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