# Siegel 2023: Cancer statistics, 2023

Source: https://onco.cc/key-papers/paper-siegel-cancer-statistics-2023-cacancer-2023/  
OnCo record `paper-siegel-cancer-statistics-2023-cacancer-2023` (Key paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The American Cancer Society's annual US report for 2023 projected about 1.96 million new cancer cases, reported a continued fall in the cancer death rate, and flagged rising prostate cancer diagnoses at advanced stage alongside a steep fall in cervical cancer among young women vaccinated against HPV.

## Summary

Siegel, Miller, Wagle and Jemal projected 1,958,310 new cancer cases and 609,820 cancer deaths in the United States for 2023. The cancer death rate had fallen 33% since 1991, an estimated 3.8 million deaths averted. The report noted that prostate cancer incidence had risen by about 3% a year from 2014 to 2019 after a decade of decline, driven by advanced-stage disease, and that cervical cancer incidence in women aged 20 to 24 had fallen by 65% from 2012 to 2019, consistent with HPV vaccination.

## Fields

- Kind: Key paper
- Last checked: 2026-09-08
- Journal: CA: A Cancer Journal for Clinicians
- Year: 2023
- DOI: 10.3322/caac.21763
- Authors: Siegel RL, Miller KD, Wagle NS, Jemal A.
- Findings: Projected 1,958,310 new cancer cases and 609,820 cancer deaths in the United States in 2023.; Cancer death rate down 33% since 1991, about 3.8 million deaths averted.; Prostate cancer incidence rising about 3% a year from 2014 to 2019, mostly advanced-stage disease.; Cervical cancer incidence in women aged 20 to 24 down 65% from 2012 to 2019.
- What it means: This edition supplied two widely quoted signals: the first population-level evidence of HPV vaccination preventing cervical cancer in the United States, and the warning that reduced PSA screening was shifting prostate cancer towards later diagnosis.
- Caveats: Projections rather than counts.; US-specific; the prostate finding relates to US screening practice.

## Sources

- Full text (DOI): https://doi.org/10.3322/caac.21763
- ACS Cancer Facts and Figures: https://www.cancer.org/research/cancer-facts-statistics.html

## Connected records

- key papers: [Jemal 2007: Cancer statistics, 2007](https://onco.cc/key-papers/paper-jemal-cancer-statistics-2007-cacancer-2007/), [Jemal 2008: Cancer statistics, 2008](https://onco.cc/key-papers/paper-jemal-cancer-statistics-2008-cacancer-2008/), [Jemal 2009: Cancer statistics, 2009](https://onco.cc/key-papers/paper-jemal-cancer-statistics-2009-cacancer-2009/), [Jemal 2010: Cancer statistics, 2010](https://onco.cc/key-papers/paper-jemal-cancer-statistics-2010-cacancer-2010/), [Siegel 2013: Cancer statistics, 2013](https://onco.cc/key-papers/paper-siegel-cancer-statistics-2013-cacancer-2013/), [Siegel 2014: Cancer statistics, 2014](https://onco.cc/key-papers/paper-siegel-cancer-statistics-2014-cacancer-2014/), [Siegel 2024: Cancer statistics, 2024, the American Cancer Society's annual US report](https://onco.cc/key-papers/paper-siegel-cancer-statistics-2024-cacancer-2024/)
- cancers: [Cervical cancer](https://onco.cc/cancers/cervical/), [Prostate cancer](https://onco.cc/cancers/prostate/)
- terms: [Incidence versus prevalence](https://onco.cc/terms/incidence-vs-prevalence/), [Mortality](https://onco.cc/terms/mortality/)

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