# Angiosarcoma (review)

Source: https://onco.cc/key-papers/paper-young-angiosarcoma-review-lancet-oncol-2010/  
OnCo record `paper-young-angiosarcoma-review-lancet-oncol-2010` (Key paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

This review summarises the epidemiology, subtypes (including radiation- and lymphoedema-associated forms), surgery, radiotherapy and chemotherapy of angiosarcoma, and why outcomes remain poor.

## Summary

Review covering the presentation and risk factors of angiosarcoma at different sites, pathology, staging, wide surgical excision with radiotherapy, systemic therapy with anthracyclines and taxanes, anti-angiogenic agents, and prognostic factors.

## Fields

- Kind: Key paper
- Last checked: 2026-09-17
- Journal: The Lancet Oncology
- Year: 2010
- DOI: 10.1016/S1470-2045(10)70023-1
- Authors: Young RJ, Brown NJ, Reed MW, et al.
- What it means: The angiosarcoma page's structure by site and by aetiology (cutaneous, radiation-associated breast, visceral) follows this review.
- Caveats: Predates immunotherapy data in cutaneous angiosarcoma.

## Sources

- Lancet Oncol 2010: https://doi.org/10.1016/S1470-2045(10)70023-1
- PubMed: https://pubmed.ncbi.nlm.nih.gov/20537949/

## Connected records

- cancers: [Angiosarcoma](https://onco.cc/cancers/angiosarcoma/)
- journals: [The Lancet Oncology](https://onco.cc/journals/lancet-oncology/)

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