# PERCIST (PET response criteria in solid tumours)

Source: https://onco.cc/terms/percist/  
OnCo record `percist` (Term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

PERCIST judges response by how much sugar a tumour takes up on a PET scan rather than by its size, with a fall of 30% or more counting as a response.

## Summary

Wahl and colleagues (Journal of Nuclear Medicine 2009) reviewed the limits of size-based criteria, which change little in effective treatment of lymphoma, sarcoma, liver cancer, mesothelioma and GIST, and proposed PERCIST 1.0. It measures lean-body-mass standardised uptake value in a fixed small region over the most active tumour, compares it with normal liver, treats the change as a continuous measure, requires a fall of 30% or more for response, and defers to RECIST 1.1 for tumours that do not take up FDG.

## Fields

- Kind: Term
- Last checked: 2026-11-04
- Also known as: PERCIST; PERCIST 1.0; PET Response Criteria in Solid Tumors

## Sources

- Wahl et al., From RECIST to PERCIST: evolving considerations for PET response criteria in solid tumors (J Nucl Med 2009): https://doi.org/10.2967/jnumed.108.057307

## Connected records

- terms: [Choi criteria (GIST response on CT)](https://onco.cc/terms/choi-criteria/), [Deauville five-point scale](https://onco.cc/terms/deauville-score/), [EORTC PET response recommendations (1999)](https://onco.cc/terms/eortc-pet-1999/), [RECIST](https://onco.cc/terms/recist/)
- technologies: [FDG PET](https://onco.cc/technologies/fdg-pet/), [Quantitative imaging biomarkers (RECIST, PERCIST, SUV, ADC)](https://onco.cc/technologies/quantitative-imaging-biomarkers/)

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