# Persephone Biosciences

Source: https://onco.cc/companies/persephone-biosciences/  
OnCo record `persephone-biosciences` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Persephone studies the gut bacteria of cancer patients and designs live bacterial medicines meant to make immunotherapy work for more people.

## Summary

Persephone Biosciences develops live biotherapeutic products that modulate gut microbial metabolism, using systems and synthetic biology to understand which microbiome features track with response to cancer immunotherapy. It ran the ARGONAUT observational study collecting stool and blood from patients with colorectal, pancreatic, lung and other cancers on checkpoint inhibitors to build that map, and has a separate infant microbiome programme. Oncology programmes are preclinical or early clinical; no round amounts are recorded here because none was fetched from a primary source.

## Fields

- Kind: Company
- Last checked: 2026-09-10
- Tags: yc
- HQ: San Diego, CA
- Type: biotech
- Website: https://persephonebiosciences.com

## Sources

- Y Combinator profile: https://www.ycombinator.com/companies/persephone-biosciences
- Official website: https://persephonebiosciences.com

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)
- fronts: [Immunotherapy](https://onco.cc/fronts/immunotherapy/), [Prevention & Risk](https://onco.cc/fronts/prevention/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- companies: [Y Combinator](https://onco.cc/companies/y-combinator/)

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JSON: https://onco.cc/api/v1/entities/persephone-biosciences.json