# Philippe Moreau

Source: https://onco.cc/people/philippe-moreau/  
OnCo record `philippe-moreau` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Led MajesTEC-1 and CASSIOPEIA, bringing the first bispecific antibody and daratumumab quadruplets to myeloma.

## Summary

Philippe Moreau (Nantes) was principal investigator of MajesTEC-1, the pivotal trial of teclistamab, the first BCMA-directed bispecific antibody approved for relapsed myeloma, and of CASSIOPEIA, which established daratumumab with bortezomib-thalidomide-dexamethasone in transplant-eligible patients. He has led IFM trials for two decades including the IFM 2009 transplant study and is a past chair of the IFM.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Tags: myeloma; bispecific; trialist
- Role: Head of the Hematology Department, University Hospital Hôtel-Dieu, Nantes
- Specialisms: Multiple myeloma; Bispecific antibodies; Daratumumab combinations; Transplant-eligible myeloma

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Moreau%20P%5BAuthor%5D%20myeloma%20teclistamab%20OR%20daratumumab

## Connected records

- cancers: [Multiple myeloma](https://onco.cc/cancers/multiple-myeloma/)
- technologies: [Bispecific antibodies](https://onco.cc/technologies/bispecific-antibody/), [T-cell engagers (bispecific)](https://onco.cc/technologies/t-cell-engager/)
- targets: [BCMA](https://onco.cc/targets/bcma/), [CD3](https://onco.cc/targets/cd3/), [CD38](https://onco.cc/targets/cd38/)
- drugs: [Teclistamab](https://onco.cc/drugs/teclistamab/)
- institutions: [Nantes University Hospital (CHU de Nantes)](https://onco.cc/institutions/chu-nantes/)
- trials: [CASSIOPEIA](https://onco.cc/trials/cassiopeia/), [MajesTEC-1](https://onco.cc/trials/majestec-1/), [MajesTEC-3](https://onco.cc/trials/majestec-3/)
- key papers: [MajesTEC-1: teclistamab, an off-the-shelf BCMA bispecific antibody, in heavily pretreated myeloma](https://onco.cc/key-papers/paper-majestec-1-teclistamab-nejm-2022/)

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