# Princess Margaret Cancer Centre

Source: https://onco.cc/institutions/princess-margaret/  
OnCo record `princess-margaret` (Institution). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Princess Margaret is Canada's leading cancer centre and a pioneer in immunotherapy and cancer stem cell research.

## Summary

Princess Margaret Cancer Centre in Toronto is Canada's leading cancer centre and ranks ninth in the Newsweek/Statista oncology list. It is where John E. Dick's group identified cancer stem cells, and it runs a major phase 1 unit under Lillian L. Siu alongside tumour-infiltrating lymphocyte and radiation medicine research, with Tak W. Mak, Pamela S. Ohashi and Aaron D. Schimmer among its scientists. OnCo links it to the CHALLENGE colon cancer exercise trial, to cBioPortal, to the cancer stem cell and phenotypic plasticity pathway, and to Ontario Health, the Ontario Institute for Cancer Research and the Canadian Cancer Society. Whether stem cell biology can yet be turned into treatments patients feel is still open. Its people page shows who to read.

## Fields

- Kind: Institution
- Last checked: 2026-09-04
- City: Toronto, CA
- Type: cancer-center
- Website: https://www.uhn.ca/PrincessMargaret

## Sources

- Wikipedia: https://en.wikipedia.org/wiki/Princess_Margaret_Cancer_Centre
- Official website: https://www.uhn.ca/PrincessMargaret

## Connected records

- people: [A. Keith Stewart](https://onco.cc/people/keith-stewart/), [Aaron D. Schimmer](https://onco.cc/people/aaron-schimmer/), [Amit M. Oza](https://onco.cc/people/amit-oza/), [Ian F. Tannock](https://onco.cc/people/ian-tannock/), [John E. Dick](https://onco.cc/people/john-dick/), [Lillian L. Siu](https://onco.cc/people/lillian-siu/), [Natasha B. Leighl](https://onco.cc/people/natasha-leighl/), [Pamela S. Ohashi](https://onco.cc/people/pamela-ohashi/), [Tak W. Mak](https://onco.cc/people/tak-mak/), [Trevor J. Pugh](https://onco.cc/people/trevor-pugh/)
- key papers: [A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns](https://onco.cc/key-papers/paper-notta-punctuated-evolution-pancreatic-nature-2016/), [Association of distinct mutational signatures with correlates of increased immune activity in pancreatic ductal adenocarcinoma](https://onco.cc/key-papers/paper-connor-mutational-signatures-immune-pancreatic-jama-oncol-2017/), [GATA6 expression distinguishes classical and basal-like subtypes in advanced pancreatic cancer](https://onco.cc/key-papers/paper-okane-gata6-basal-like-compass-ccr-2020/), [Genomics-driven precision medicine for advanced pancreatic cancer: early results from the COMPASS trial](https://onco.cc/key-papers/paper-aung-compass-early-results-ccr-2018/), [Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers](https://onco.cc/key-papers/paper-golan-brca-pancreatic-platinum-survival-bjc-2014/), [Spatially confined sub-tumor microenvironments in pancreatic cancer](https://onco.cc/key-papers/paper-grunwald-subtme-pancreatic-cell-2021/), [Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution](https://onco.cc/key-papers/paper-chan-seng-yue-pancreatic-transcription-phenotypes-nat-genet-2020/)
- collections: [cBioPortal for Cancer Genomics](https://onco.cc/collections/cbioportal/)
- ideas: [Broad research consent as a routine step of the cancer pathway](https://onco.cc/ideas/idea-data-consent-in-the-pathway/), [Take faecal transplant plus immunotherapy to a definitive trial](https://onco.cc/ideas/idea-bio2-fmt-plus-checkpoint-phase3/)
- pathways: [Cancer stem cells & phenotypic plasticity](https://onco.cc/pathways/cancer-stem-cells-plasticity/)
- trials: [CHALLENGE (CCTG CO.21)](https://onco.cc/trials/challenge/)
- institutions: [Canadian Cancer Society](https://onco.cc/institutions/canadian-cancer-society/), [Health Canada](https://onco.cc/institutions/health-canada/), [Ontario Health (Cancer Care Ontario)](https://onco.cc/institutions/ontario-health-cancer-care-ontario/), [Ontario Institute for Cancer Research](https://onco.cc/institutions/oicr/), [Sunnybrook Odette Cancer Centre](https://onco.cc/institutions/sunnybrook-odette/), [Terry Fox Research Institute](https://onco.cc/institutions/terry-fox-research-institute/), [The Hospital for Sick Children (SickKids)](https://onco.cc/institutions/sickkids/)

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JSON: https://onco.cc/api/v1/entities/princess-margaret.json