# PSA doubling time

Source: https://onco.cc/terms/psa-doubling-time/  
OnCo record `psa-doubling-time` (Term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

How long the PSA takes to double, used to tell a slow rise from a fast one.

## Summary

NICE NG131 asks for it to be estimated from at least three measurements over at least six months when the PSA rises after treatment, and uses a doubling time of less than three months as one of the three reasons to start hormone therapy for a biochemical relapse. The speed carries more information than the number itself, which is why a single raised reading is not treated as an event.

## Fields

- Kind: Term
- Last checked: 2026-09-25
- Also known as: PSADT

## Sources

- NICE NG131: prostate cancer, diagnosis and management: https://www.nice.org.uk/guidance/ng131/chapter/Recommendations

## Connected records

- terms: [Metastasis-free survival (MFS)](https://onco.cc/terms/metastasis-free-survival/)
- cancers: [Non-metastatic castration-resistant prostate cancer](https://onco.cc/cancers/prostate-nmcrpc/), [Prostate cancer](https://onco.cc/cancers/prostate/)
- trials: [EMBARK](https://onco.cc/trials/embark/)

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JSON: https://onco.cc/api/v1/entities/psa-doubling-time.json