# PTK7

Source: https://onco.cc/targets/ptk7/  
OnCo record `ptk7` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

PTK7 is a cell-surface protein being studied as an address for cancer-directed treatments.

## Summary

AACR 2024 abstract 2616 describes PTK7 and TROP2 as the two antigens bound by BCG033. The cited antibody-drug conjugate evidence is from cell and xenograft models; it does not establish clinical benefit or a companion diagnostic.

## Fields

- Kind: Target
- Last checked: 2026-10-06
- Symbol: PTK7
- Class: surface-antigen
- Biology: Cell-surface antigen studied for binding and internalization of antibody-drug conjugates; the cited BCG033 abstract describes co-targeting with TROP2.

## Sources

- AACR 2024 BCG033 abstract: https://doi.org/10.1158/1538-7445.am2024-2616
- HGNC PTK7 approved gene record: https://rest.genenames.org/fetch/symbol/PTK7

## Connected records

- drugs: [BCG033](https://onco.cc/drugs/bcg033/)

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JSON: https://onco.cc/api/v1/entities/ptk7.json