# Quemliclustat

Source: https://onco.cc/drugs/quemliclustat/  
OnCo record `quemliclustat` (Treatment). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Quemliclustat is an experimental investigational agent whose form is not stated in the registry from Arcus Biosciences in phase 3 trials for pancreatic ductal adenocarcinoma and non-small-cell lung cancer, with its target not yet stated publicly.

## Summary

Quemliclustat is an investigational agent whose form is not stated in the registry developed by Arcus Biosciences and Gilead Sciences. The sponsor describes its target as adenosine axis, which OnCo does not yet have a target page for. It is the investigational product in 3 recruiting or active industry-led phase 2 and phase 3 interventional cancer trials, including the phase 3 study NCT06608927 (Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma), in pancreatic ductal adenocarcinoma and non-small-cell lung cancer. The largest, NCT06608927, plans to enrol 610 participants with primary completion expected 2030-11-30. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.

## Fields

- Kind: Treatment
- Status: phase-3
- Last checked: 2026-09-11
- Tags: pipeline; ctgov-ingest
- Modality: not stated (registered as a drug or biological on ClinicalTrials.gov)
- Mechanism: Mechanism not stated in the ClinicalTrials.gov record or on the sponsor's pipeline page.

## Sources

- ClinicalTrials.gov: trials of Quemliclustat: https://clinicaltrials.gov/search?intr=Quemliclustat
- Sponsor page: https://www.arcusbio.com

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Pancreatic ductal adenocarcinoma](https://onco.cc/cancers/pancreatic/)
- companies: [Arcus Biosciences](https://onco.cc/companies/arcus-biosciences/), [Gilead Sciences (incl. Kite)](https://onco.cc/companies/gilead/)
- trials: [A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies](https://onco.cc/trials/nct05329766/), [Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma](https://onco.cc/trials/nct06608927/), [Study With Various Immunotherapy Treatments in Participants With Lung Cancer](https://onco.cc/trials/nct05676931/)

---
JSON: https://onco.cc/api/v1/entities/quemliclustat.json