# Quest Comprehensive Hereditary Cancer Panel (66 genes)

Source: https://onco.cc/drugs/quest-hereditary-cancer-panel/  
OnCo record `quest-hereditary-cancer-panel` (Test). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Quest Diagnostics' test of 66 genes linked to inherited cancer risk, ordered through a clinician.

## Summary

Registered in the NIH Genetic Testing Registry as GTR000592394.4 (updated 25 June 2024) by Quest Diagnostics Nichols Institute San Juan Capistrano (CLIA 05D0643352), order code 38600: 66 genes, including the Fanconi genes FANCA, FANCC and FANCM, BLM, NTHL1, POLE, POLD1, FLCN, MET, PTCH1 and SUFU alongside the breast, ovarian and Lynch genes. GTR does not record a development type for this entry; it is not among the FDA-authorised hereditary cancer products.

## Fields

- Kind: Test
- Status: established
- Last checked: 2026-11-04
- Tags: test; hereditary
- Brand: Comprehensive Hereditary Cancer Panel
- Modality: Germline hereditary cancer sequencing panel test
- Mechanism: Next-generation sequencing of 66 hereditary cancer genes in germline DNA.

## Sources

- NIH Genetic Testing Registry GTR000592394.4: https://www.ncbi.nlm.nih.gov/gtr/tests/592394/
- NIH Genetic Testing Registry data file (test_version.gz): https://ftp.ncbi.nlm.nih.gov/pub/GTR/data/test_version.gz

## Connected records

- technologies: [Germline (hereditary) testing](https://onco.cc/technologies/germline-testing/)
- targets: [BLM](https://onco.cc/targets/blm/), [BRCA1 / BRCA2 (HRD)](https://onco.cc/targets/brca/), [FANCA](https://onco.cc/targets/fanca/), [FLCN](https://onco.cc/targets/flcn/), [MET](https://onco.cc/targets/met/), [MLH1](https://onco.cc/targets/mlh1/), [MSH2](https://onco.cc/targets/msh2/), [NTHL1](https://onco.cc/targets/nthl1/), [PALB2](https://onco.cc/targets/palb2/)
- companies: [Quest Diagnostics](https://onco.cc/companies/quest-diagnostics/)
- terms: [Birt-Hogg-Dubé syndrome](https://onco.cc/terms/birt-hogg-dube-syndrome/), [Hereditary cancer syndromes](https://onco.cc/terms/hereditary-cancer-syndromes/), [Lynch syndrome](https://onco.cc/terms/lynch-syndrome/), [NTHL1-associated polyposis](https://onco.cc/terms/nthl1-associated-polyposis/)

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