# Roman Thomas

Source: https://onco.cc/people/roman-thomas/  
OnCo record `roman-thomas` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Roman Thomas is a cancer genomicist who mapped the genomes of small-cell lung cancer.

## Summary

Roman Thomas is Director of the Department of Translational Genomics at the University of Cologne (CIO). A cancer genomicist, his specialisms are cancer genomics, small-cell lung cancer and lung cancer biology, with a focus on TP53. He led the comprehensive genomic profiling of small-cell lung cancer, reported in Nature, which showed near-universal loss of TP53 and RB1 in the disease. He has also characterised squamous lung cancer and the neuroendocrine transformation of non-small-cell lung cancer. His publications are listed on PubMed.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Director, Department of Translational Genomics, University of Cologne
- Specialisms: Cancer genomics; Small-cell lung cancer; Lung cancer biology

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Thomas%20RK%5BAuthor%5D%20small%20cell%20lung%20cancer%20genomic

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- targets: [TP53](https://onco.cc/targets/tp53/)
- institutions: [Uniklinik Köln (CIO)](https://onco.cc/institutions/uniklinik-koeln/)
- key papers: [CD74-NRG1 fusions in lung adenocarcinoma](https://onco.cc/key-papers/paper-fernandez-cuesta-cd74-nrg1-fusion-lung-cancer-discov-2014/), [Comprehensive genomic profiles of small cell lung cancer](https://onco.cc/key-papers/paper-george-sclc-genomic-profiles-nature-2015/), [Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer](https://onco.cc/key-papers/paper-weiss-fgfr1-amplification-squamous-lung-sci-transl-med-2010/)

---
JSON: https://onco.cc/api/v1/entities/roman-thomas.json