# Sagar Lonial

Source: https://onco.cc/people/sagar-lonial/  
OnCo record `sagar-lonial` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Led SIRIUS and the DREAMM programme, bringing daratumumab monotherapy and the BCMA ADC belantamab to myeloma.

## Summary

Sagar Lonial led SIRIUS, the trial that won daratumumab its first approval as monotherapy in relapsed myeloma, and DREAMM-2, the pivotal trial of belantamab mafodotin, the first BCMA-directed ADC. He has led the Emory series showing near-universal deep responses to RVd induction and chairs the myeloma committee of the SWOG cooperative group.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Tags: myeloma; adc; swog
- Role: Chair of Hematology and Medical Oncology and Chief Medical Officer, Winship Cancer Institute of Emory University
- Specialisms: Multiple myeloma; Antibody-drug conjugates; Daratumumab; High-risk myeloma

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Lonial%20S%5BAuthor%5D%20myeloma%20belantamab%20OR%20daratumumab

## Connected records

- cancers: [Multiple myeloma](https://onco.cc/cancers/multiple-myeloma/)
- technologies: [Antibody-drug conjugate (ADC)](https://onco.cc/technologies/adc/), [Monoclonal antibodies](https://onco.cc/technologies/monoclonal-antibody/)
- targets: [BCMA](https://onco.cc/targets/bcma/), [CD38](https://onco.cc/targets/cd38/)
- drugs: [Belantamab mafodotin](https://onco.cc/drugs/belantamab-mafodotin/)
- institutions: [Winship Cancer Institute of Emory University](https://onco.cc/institutions/emory-winship/)
- trials: [DREAMM-7](https://onco.cc/trials/dreamm-7/), [DREAMM-8](https://onco.cc/trials/dreamm-8/)

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