# Sergio Roman-Roman

Source: https://onco.cc/people/sergio-roman-roman/  
OnCo record `sergio-roman-roman` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Directs the translational research department that developed models and targets for uveal melanoma.

## Summary

Sergio Roman-Roman is Director of Translational Research at Institut Curie in Paris. His specialisms are translational research, uveal melanoma and preclinical models, including patient-derived xenograft platforms. He directs the department that developed models and targets for uveal melanoma. His papers include the establishment of cell lines recapitulating the genetic landscape of uveal melanoma with preclinical validation of mTOR as a target, a Cancer Discovery study linking SF3B1 mutations to alternative splicing in uveal melanoma, and a Cancer Cell integrative analysis identifying four molecular and clinical subsets of the disease. His publications are listed on PubMed.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Director of Translational Research, Institut Curie
- Specialisms: Translational research; Uveal melanoma; Preclinical models

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Roman-Roman%20S%5BAuthor%5D%20uveal%20melanoma

## Connected records

- cancers: [Melanoma](https://onco.cc/cancers/melanoma/)
- technologies: [Patient-derived xenografts](https://onco.cc/technologies/pdx-models/)
- institutions: [Institut Curie](https://onco.cc/institutions/institut-curie/)
- journals: [Molecular oncology](https://onco.cc/journals/molecular-oncology/)

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