# Step Pharma

Source: https://onco.cc/companies/step-pharma/  
OnCo record `step-pharma` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Step Pharma is a French biotech whose oral drug STP938 blocks CTPS1, an enzyme that dividing lymphocytes depend on, to treat T-cell and B-cell lymphomas.

## Summary

Step Pharma develops selective inhibitors of cytidine triphosphate synthase 1 (CTPS1), an enzyme discovered through a rare human immunodeficiency to be essential for lymphocyte proliferation but dispensable for most other cells. STP938 is an oral CTPS1 inhibitor in a phase 1/2 trial in relapsed or refractory T-cell and B-cell lymphomas, and the mechanism is also being explored in autoimmune disease.

## Fields

- Kind: Company
- Last checked: 2026-09-17
- Also known as: Step Pharma SAS
- Tags: drug-maker
- HQ: Saint-Genis-Pouilly
- Type: biotech

## Connected records

- drugs: [STP938](https://onco.cc/drugs/stp938/)

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JSON: https://onco.cc/api/v1/entities/step-pharma.json