# Synaffix (Lonza)

Source: https://onco.cc/companies/synaffix/  
OnCo record `synaffix` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Licensor of the GlycoConnect site-specific ADC conjugation platform, now part of Lonza and used by dozens of ADC developers.

## Summary

Synaffix, based in Oss in the Netherlands and now part of Lonza, licenses the GlycoConnect site-specific antibody-drug conjugate conjugation platform, used by dozens of ADC developers. GlycoConnect attaches payloads at the conserved Asn297 glycan to give a defined drug-to-antibody ratio, HydraSpace and toxSYN complete the platform, Lonza acquired the company in 2023 and integrated it into an end-to-end ADC service, and 2026 brought multi-target licences with Sidewinder for bispecific ADCs and with Engitix. OnCo links it to site-specific conjugation and linker chemistry, ADCs and bispecific ADCs, to ADC bioconjugation manufacturing, to Lonza, and to the idea of platform designation for linker-payloads. Whether a shared conjugation platform can earn regulatory credit that carries across products is the open question. Lonza has its own page.

## Fields

- Kind: Company
- Last checked: 2026-09-04
- HQ: Oss
- Type: biotech
- Website: https://synaffix.com

## Sources

- Lonza ADC technology platform: https://www.lonza.com/advanced-synthesis/adc-technologies-platform

## Connected records

- fronts: [Antibody-Drug Conjugates](https://onco.cc/fronts/adcs/), [Drug Discovery Platforms](https://onco.cc/fronts/drug-discovery/)
- technologies: [ADC bioconjugation manufacturing (CDMOs)](https://onco.cc/technologies/adc-cdmo-manufacturing/), [Antibody-drug conjugate (ADC)](https://onco.cc/technologies/adc/), [Bispecific ADC](https://onco.cc/technologies/bispecific-adc/), [Site-specific conjugation & linker chemistry](https://onco.cc/technologies/site-specific-conjugation/)
- ideas: [Platform designation for ADC linker-payloads so manufacturing data carry across](https://onco.cc/ideas/idea-reg-adc-platform-designation/)
- companies: [Lonza](https://onco.cc/companies/lonza/)

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