# SynsoryBio

Source: https://onco.cc/companies/synsorybio/  
OnCo record `synsorybio` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

SynsoryBio builds protein drugs with built-in if-then logic: they stay switched off until they sense they are in diseased tissue, a way to make immune-activating and cell-killing biologics usable at doses that would otherwise harm healthy tissue. It is preclinical, with a small team and no recorded financing.

## Summary

SynsoryBio is creating conditionally activated protein therapeutics that sense their location in the body and become active only at diseased tissue, a way to widen the therapeutic window of immune agonists and cytotoxic biologics whose toxicity to healthy tissue limits their dose in cancer and autoimmune disease. The approach is related to masked or protease-activated biologics. The company is tagged oncology in the YC directory and is preclinical with a very small team; no sourced financing rounds are recorded.

## Fields

- Kind: Company
- Last checked: 2026-09-10
- Tags: yc
- HQ: Boston, MA
- Type: biotech
- Website: https://www.synsorybio.com

## Sources

- Y Combinator profile: https://www.ycombinator.com/companies/synsorybio
- Official website: https://www.synsorybio.com

## Connected records

- fronts: [Immunotherapy](https://onco.cc/fronts/immunotherapy/), [Targeted Therapy](https://onco.cc/fronts/targeted-therapy/)
- technologies: [Cytokines & engineered cytokines](https://onco.cc/technologies/cytokine-therapy/), [Masked / conditionally active ADC](https://onco.cc/technologies/masked-adc/)
- companies: [Y Combinator](https://onco.cc/companies/y-combinator/)

---
JSON: https://onco.cc/api/v1/entities/synsorybio.json