# UGT1A

Source: https://onco.cc/targets/ugt1a/  
OnCo record `ugt1a` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

UGT1A (UDP glucuronosyltransferase family 1 member A complex locus) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer.

## Summary

UniProt has no function text for this gene; HGNC names it "UDP glucuronosyltransferase family 1 member A complex locus".

CIViC holds 1 clinical evidence item and 0 assertions across 2 variants, naming Ganetespib.

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: UDP glucuronosyltransferase family 1 member A complex locus; UGT1A@
- Tags: cancer-genes-wave
- Symbol: UGT1A
- Class: other
- Biology: UniProt has no function text for this gene; HGNC names it "UDP glucuronosyltransferase family 1 member A complex locus". Locus 2q37 (HGNC).
- Where found: Colorectal cancer: CIViC evidence names this disease

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC lists 1 therapies; CIViC holds 1 clinical evidence items on its variants. Evidence tier "clinical-evidence" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:12529: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12529
- NCBI Gene 7361: https://www.ncbi.nlm.nih.gov/gene/7361

## Connected records

- collections: [CIViC](https://onco.cc/collections/civic/)
- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)

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JSON: https://onco.cc/api/v1/entities/ugt1a.json