# USC Norris Comprehensive Cancer Center

Source: https://onco.cc/institutions/usc-norris/  
OnCo record `usc-norris` (Institution). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

USC Norris was one of the first eight NCI comprehensive cancer centres in 1973; Peter Jones's work here on 5-azacytidine and DNA methylation founded cancer epigenetic therapy, Heinz-Josef Lenz leads its gastrointestinal and SWOG colorectal trials, and its Multiethnic Cohort Study tracks cancer risk across ethnic groups.

## Summary

USC Norris was among the first eight centres to receive NCI comprehensive designation in 1973. Peter Jones's work here on 5-azacytidine and DNA methylation in the early 1980s founded the field of cancer epigenetic therapy. Heinz-Josef Lenz leads GI oncology and SWOG colorectal trials, and the Multiethnic Cohort Study run with the University of Hawai'i is one of the largest studies of cancer risk across ethnic groups. The centre serves Los Angeles County's diverse population and runs a broad early-phase trial programme.

## Fields

- Kind: Institution
- Last checked: 2026-09-09
- City: Los Angeles, CA, US
- Type: cancer-center
- NCI designation: comprehensive
- Website: https://uscnorriscancer.usc.edu

## Sources

- Wikipedia: https://en.wikipedia.org/wiki/USC_Norris_Comprehensive_Cancer_Center
- USC Norris Comprehensive Cancer Center: https://uscnorriscancer.usc.edu
- Clinical trials: https://uscnorriscancer.usc.edu/clinical-trials/

## Connected records

- cancers: [Acute myeloid leukaemia](https://onco.cc/cancers/aml/), [Colorectal cancer](https://onco.cc/cancers/colorectal/), [Myelodysplastic syndromes / neoplasms (MDS)](https://onco.cc/cancers/mds/)
- fronts: [Epigenetic & Transcriptional Therapy](https://onco.cc/fronts/epigenetics/)
- technologies: [DNA methylation profiling](https://onco.cc/technologies/methylation-profiling/), [Epigenetic drugs (HDAC, DNMT, EZH2, IDH, menin, BET)](https://onco.cc/technologies/epigenetic-drugs/)
- drugs: [Azacitidine](https://onco.cc/drugs/azacitidine/)
- companies: [SWOG Cancer Research Network](https://onco.cc/companies/swog/)
- institutions: [National Cancer Institute (NIH)](https://onco.cc/institutions/nci/), [University of Hawai'i Cancer Center](https://onco.cc/institutions/hawaii-cancer-center/)
- people: [Heinz-Josef Lenz](https://onco.cc/people/heinz-josef-lenz/)

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JSON: https://onco.cc/api/v1/entities/usc-norris.json