# West Japan Oncology Group

Source: https://onco.cc/companies/wjog/  
OnCo record `wjog` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Japan's second national cooperative group, born in thoracic oncology; its WJTOG3405 trial helped establish EGFR inhibitors as first-line lung cancer therapy.

## Summary

Founded in 2000 as the West Japan Thoracic Oncology Group and renamed WJOG in 2008 as it expanded into gastrointestinal, breast and other cancers. WJTOG3405 (gefitinib versus cisplatin-docetaxel in EGFR-mutant NSCLC) was one of the two Japanese phase 3 trials that made EGFR testing and first-line targeted therapy the standard worldwide. WJOG runs investigator-initiated trials of targeted agents, immunotherapy and chemotherapy across Japan's university and cancer centre hospitals and collaborates with JCOG and with Asian and Western groups. Its committees cover thoracic, gastrointestinal, breast, gynaecologic and genitourinary cancers.

## Fields

- Kind: Company
- Last checked: 2026-09-09
- Also known as: WJOG; West Japan Thoracic Oncology Group; WJTOG
- Tags: cooperative-group
- HQ: Osaka
- Type: cooperative-group
- Website: https://www.wjog.jp

## Notes

- Thoracic oncology (WJTOG3405)
- Gastrointestinal oncology
- Breast oncology
- Investigator-initiated trials of targeted therapy and immunotherapy

## Sources

- WJOG: https://www.wjog.jp

## Connected records

- drugs: [Osimertinib](https://onco.cc/drugs/osimertinib/)
- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/), [Gastric & gastro-oesophageal junction cancer](https://onco.cc/cancers/gastric/), [HER2-positive breast cancer](https://onco.cc/cancers/breast-her2-positive/), [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/), [Small-molecule kinase inhibitors](https://onco.cc/technologies/kinase-inhibitors/)
- companies: [Japan Clinical Oncology Group (JCOG)](https://onco.cc/companies/jcog/)
- institutions: [Japanese Society of Medical Oncology](https://onco.cc/institutions/jsmo/), [National Cancer Center Hospital](https://onco.cc/institutions/ncc-japan/)
- terms: [Oncogene addiction](https://onco.cc/terms/oncogene-addiction/)
- trials: [Takahashi trial: prophylactic cranial irradiation with MRI surveillance in extensive-stage small-cell lung cancer](https://onco.cc/trials/takahashi-pci/)
- people: [Nobuyuki Yamamoto](https://onco.cc/people/nobuyuki-yamamoto/)

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JSON: https://onco.cc/api/v1/entities/wjog.json