{"id":"dhx9","name":"DHX9","symbol":"DHX9","route":"/targets/dhx9/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2750","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000135829","uniprot":"https://www.uniprot.org/uniprotkb/Q08211/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q08211","open-targets":"https://platform.opentargets.org/target/ENSG00000135829","civic":"https://civicdb.org/genes/1660/summary","oncokb":"https://www.oncokb.org/gene/DHX9","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=DHX9","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=DHX9","depmap":"https://depmap.org/portal/gene/DHX9?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000135829-DHX9","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/1660","omim":"https://www.omim.org/entry/603115"}],"products":[{"id":"atx-559","name":"ATX-559","status":"phase-1","modality":"Oral small molecule","route":"/drugs/atx-559/"}],"trials":[{"id":"nct06625515","name":"First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers","nct":"NCT06625515","phase":"1","status":"historic"}],"pathways":[],"companies":["accent-therapeutics"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}