{"id":"gpr65","name":"GPR65","symbol":"GPR65","route":"/targets/gpr65/","asOf":"2026-11-03","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4517","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000140030","uniprot":"https://www.uniprot.org/uniprotkb/Q8IYL9/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q8IYL9","open-targets":"https://platform.opentargets.org/target/ENSG00000140030","civic":"https://civicdb.org/genes/8477/summary","oncokb":"https://www.oncokb.org/gene/GPR65","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=GPR65","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=GPR65","depmap":"https://depmap.org/portal/gene/GPR65?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000140030-GPR65","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/8477","omim":"https://www.omim.org/entry/604620"}],"products":[{"id":"ptt-4256","name":"PTT-4256","status":"phase-1","modality":"Oral small molecule","route":"/drugs/ptt-4256/"}],"trials":[],"pathways":[],"companies":["pathios-therapeutics"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}