{"id":"hpk1","name":"HPK1 (MAP4K1)","symbol":"MAP4K1","route":"/targets/hpk1/","asOf":"2026-11-03","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6863","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104814","uniprot":"https://www.uniprot.org/uniprotkb/Q92918/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q92918","open-targets":"https://platform.opentargets.org/target/ENSG00000104814","civic":"https://civicdb.org/genes/11184/summary","oncokb":"https://www.oncokb.org/gene/MAP4K1","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=MAP4K1","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=MAP4K1","depmap":"https://depmap.org/portal/gene/MAP4K1?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000104814-MAP4K1","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/11184","omim":"https://www.omim.org/entry/601983"}],"products":[{"id":"cfi-402411","name":"CFI-402411","status":"phase-1","modality":"Small molecule","route":"/drugs/cfi-402411/"}],"trials":[],"pathways":[],"companies":["treadwell-therapeutics"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}