{"id":"rbm39","name":"RBM39","symbol":"RBM39","route":"/targets/rbm39/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:15923","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000131051","uniprot":"https://www.uniprot.org/uniprotkb/Q14498/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q14498","open-targets":"https://platform.opentargets.org/target/ENSG00000131051","civic":"https://civicdb.org/genes/9584/summary","oncokb":"https://www.oncokb.org/gene/RBM39","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=RBM39","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=RBM39","depmap":"https://depmap.org/portal/gene/RBM39?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000131051-RBM39","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/9584","omim":"https://www.omim.org/entry/604739"}],"products":[{"id":"rec-1245","name":"REC-1245","status":"phase-1","modality":"Protein degrader (small molecule)","route":"/drugs/rec-1245/"},{"id":"st-01156","name":"ST-01156","status":"phase-1","modality":"Oral small-molecule molecular glue degrader","route":"/drugs/st-01156/"}],"trials":[{"id":"nct07197554","name":"A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies","nct":"NCT07197554","phase":"1","status":"recruiting"}],"pathways":[],"companies":["recursion","seed-therapeutics"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}