{"entity":{"id":"1953","kind":"year","name":"1953 in oncology","aka":["1953"],"tldr":"Everything OnCo dates to 1953: 10 entries, 4 landmarks, 3 technologies, 2 approvals and 1 journal founded. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.","summary":"10 dated entries in OnCo fall in 1953: 4 landmarks, 3 technologies, 2 approvals and 1 journal founded.\n\nOf those, 10 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.\n\nEverything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.","asOf":"2026-09-25","links":[],"tags":[],"related":["1952","1954"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Generated from every dated field in the corpus, not written by hand. The groups and the fields behind them are listed in src/lib/year-groups.ts; the reader is src/lib/years.ts."],"year":1953,"events":[{"group":"approval","date":"1953","precision":"year","title":"Mercaptopurine approved in US","note":"Acute lymphoblastic leukaemia, combination maintenance therapy","from":"mercaptopurine","refs":[]},{"group":"approval","date":"1953","precision":"year","title":"Methotrexate approved in US","note":"ALL, choriocarcinoma, and later osteosarcoma, breast, head and neck, lung, lymphoma, mycosis fungoides","from":"methotrexate","refs":[]},{"group":"history","date":"1953","precision":"year","title":"Craniospinal irradiation introduced (Paterson and Farr)","note":"Medulloblastoma. First cures.","from":"medulloblastoma","refs":[]},{"group":"history","date":"1953","precision":"year","title":"Craniospinal irradiation introduced for medulloblastoma","note":"Group 3 and group 4 medulloblastoma (non-WNT/non-SHH)","from":"medulloblastoma-group-3-4","refs":[]},{"group":"history","date":"1953","precision":"year","title":"Lichtenstein unifies eosinophilic granuloma, Hand-Schuller-Christian and Letterer-Siwe disease as histiocytosis X","note":"Langerhans cell histiocytosis (LCH)","from":"langerhans-cell-histiocytosis","refs":[]},{"group":"history","date":"1953","precision":"year","title":"Lichtenstein unifies eosinophilic granuloma, Hand-Schüller-Christian and Letterer-Siwe disease as histiocytosis X","note":"Single-system Langerhans cell histiocytosis (bone, skin or one other organ)","from":"lch-single-system","refs":[]},{"group":"journal","date":"1953","precision":"year","title":"Advances in cancer research founded","note":"Elsevier (Academic Press)","from":"advances-in-cancer-research","refs":[]},{"group":"technology","date":"1953","precision":"year","title":"C-arm medical linear accelerators (TrueBeam, Versa HD and others)","note":"First use in humans or first approval, as the technology record states it.","from":"c-arm-linac","refs":[]},{"group":"technology","date":"1953","precision":"year","title":"Linac, proton system and brachytherapy machine manufacturing","note":"First use in humans or first approval, as the technology record states it.","from":"radiotherapy-equipment-manufacturing","refs":[]},{"group":"technology","date":"1953","precision":"year","title":"Tumour hypoxia: imaging and modification","note":"First use in humans or first approval, as the technology record states it.","from":"tumour-hypoxia-modification","refs":[]}]},"route":"/years/1953/","neighbours":{"year":[{"id":"1952","kind":"year","name":"1952 in oncology","route":"/years/1952/"},{"id":"1954","kind":"year","name":"1954 in oncology","route":"/years/1954/"}]}}