{"entity":{"id":"1970","kind":"year","name":"1970 in oncology","aka":["1970"],"tldr":"Everything OnCo dates to 1970: 14 entries, 5 landmarks, 4 approvals, 3 technologies and 1 company founded. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.","summary":"14 dated entries in OnCo fall in 1970: 5 landmarks, 4 approvals, 3 technologies, 1 company founded and 1 paper.\n\nOf those, 14 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.\n\nEverything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.","asOf":"2026-09-25","links":[],"tags":[],"related":["1969","1971"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Generated from every dated field in the corpus, not written by hand. The groups and the fields behind them are listed in src/lib/year-groups.ts; the reader is src/lib/years.ts."],"year":1970,"events":[{"group":"approval","date":"1970","precision":"year","title":"Floxuridine approved in US","note":"Gastrointestinal adenocarcinoma metastatic to the liver, by continuous regional intra-arterial infusion","from":"floxuridine","refs":[]},{"group":"approval","date":"1970","precision":"year","title":"Fluorouracil (5-FU) approved in US","note":"Topical: actinic keratosis and superficial basal cell carcinoma","from":"fluorouracil","refs":[]},{"group":"approval","date":"1970","precision":"year","title":"Mitotane approved in US","note":"Inoperable adrenocortical carcinoma (functional and non-functional)","from":"mitotane","refs":[]},{"group":"approval","date":"1970","precision":"year","title":"Plicamycin approved in US","note":"Disseminated testicular tumours; hypercalcaemia and hypercalciuria of malignancy. Discontinued in 2000","from":"plicamycin","refs":[]},{"group":"company","date":"1970","precision":"year","title":"GOG Foundation founded","note":"Philadelphia, PA","from":"gog-foundation","refs":[]},{"group":"history","date":"1970","precision":"year","title":"Adjuvant chemotherapy for osteosarcoma (Jaffe, Rosen) turns a 20% survival into 60%","note":"Sarcomas (soft tissue, bone, GIST)","from":"sarcoma","refs":["doxorubicin"]},{"group":"history","date":"1970","precision":"year","title":"Amputation alone cures <20%; lung metastases the rule","note":"Osteosarcoma","from":"osteosarcoma","refs":[]},{"group":"history","date":"1970","precision":"year","title":"Enzinger describes epithelioid sarcoma","note":"Epithelioid sarcoma. Named for its resemblance to carcinoma and granuloma.","from":"epithelioid-sarcoma","refs":[]},{"group":"history","date":"1970","precision":"year","title":"Mitotane approved in the United States","note":"Localised adrenocortical carcinoma (ENSAT stage I to III, resectable)","from":"localised-adrenocortical-carcinoma","refs":["mitotane"]},{"group":"history","date":"1970","precision":"year","title":"Therapy-related leukaemia recognised after alkylating agents for Hodgkin lymphoma","note":"Secondary and therapy-related acute myeloid leukaemia","from":"aml-secondary","refs":["secondary-malignancy"]},{"group":"paper","date":"1970","precision":"year","title":"The concept of immunological surveillance","note":"Burnet FM. Progress in experimental tumor research.","from":"paper-burnet-prog-exp-tumor-res","refs":[]},{"group":"technology","date":"1970","precision":"year","title":"Pharmacokinetic and pharmacodynamic modelling","note":"First use in humans or first approval, as the technology record states it.","from":"pkpd-modelling","refs":[]},{"group":"technology","date":"1970","precision":"year","title":"Radiosensitisers","note":"First use in humans or first approval, as the technology record states it.","from":"radiosensitisers","refs":[]},{"group":"technology","date":"1970","precision":"year","title":"Total body and total marrow irradiation","note":"First use in humans or first approval, as the technology record states it.","from":"total-body-irradiation","refs":[]}]},"route":"/years/1970/","neighbours":{"year":[{"id":"1969","kind":"year","name":"1969 in oncology","route":"/years/1969/"},{"id":"1971","kind":"year","name":"1971 in oncology","route":"/years/1971/"}]}}