{"entity":{"id":"1974","kind":"year","name":"1974 in oncology","aka":["1974"],"tldr":"Everything OnCo dates to 1974: 16 entries, 8 landmarks, 5 journals founded, 2 approvals and 1 paper. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.","summary":"16 dated entries in OnCo fall in 1974: 8 landmarks, 5 journals founded, 2 approvals and 1 paper.\n\nOf those, 16 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.\n\nEverything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.","asOf":"2026-09-25","links":[],"tags":[],"related":["1973","1975"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Generated from every dated field in the corpus, not written by hand. The groups and the fields behind them are listed in src/lib/year-groups.ts; the reader is src/lib/years.ts."],"year":1974,"events":[{"group":"approval","date":"1974","precision":"year","title":"Doxorubicin approved in US","note":"Broad: sarcomas, lymphomas, leukaemias, breast, and other solid tumours","from":"doxorubicin","refs":[]},{"group":"approval","date":"1974","precision":"year","title":"Mitomycin C approved in US","note":"Disseminated gastric or pancreatic adenocarcinoma (with other agents)","from":"mitomycin","refs":[]},{"group":"history","date":"1974","precision":"year","title":"Einhorn introduces cisplatin (PVB)","note":"Testicular germ cell tumours. Cure rates in metastatic disease jump from ~10% to ~60-70%.","from":"testicular","refs":["cisplatin"]},{"group":"history","date":"1974","precision":"year","title":"Goblet cell carcinoid of the appendix described as a distinct tumour","note":"Goblet cell adenocarcinoma of the appendix","from":"goblet-cell-adenocarcinoma","refs":[]},{"group":"history","date":"1974","precision":"year","title":"IESS-I: adjuvant VAC + doxorubicin raises survival from ~10% to ~60%","note":"Ewing sarcoma","from":"ewing-sarcoma","refs":["vincristine","doxorubicin","cyclophosphamide"]},{"group":"history","date":"1974","precision":"year","title":"Karapandzic describes the neurovascular flap that keeps the mouth working","note":"Lip cancer","from":"lip-cancer","refs":[]},{"group":"history","date":"1974","precision":"year","title":"Kyle defines plasma cell leukaemia at 20 percent or 2 x 10^9/L circulating plasma cells","note":"Plasma cell leukaemia","from":"plasma-cell-leukaemia","refs":[]},{"group":"history","date":"1974","precision":"year","title":"MD Anderson gives chemotherapy before surgery in inflammatory breast cancer","note":"Inflammatory breast cancer","from":"inflammatory-breast-cancer","refs":["gabriel-hortobagyi","doxorubicin"]},{"group":"history","date":"1974","precision":"year","title":"Nigro reports complete responses to fluorouracil, mitomycin and radiotherapy, sparing the anus","note":"Localised anal squamous cell carcinoma (stage I to III)","from":"localised-anal-cancer","refs":["fluorouracil","mitomycin"]},{"group":"history","date":"1974","precision":"year","title":"Nigro: chemoradiation instead of surgery","note":"Anal cancer (squamous cell carcinoma). Three patients with complete response to 5-FU, mitomycin and radiation; abdominoperineal resection abandoned as first treatment.","from":"anal","refs":["fluorouracil","mitomycin"]},{"group":"journal","date":"1974","precision":"year","title":"Cancer treatment reviews founded","note":"Elsevier","from":"cancer-treatment-reviews","refs":[]},{"group":"journal","date":"1974","precision":"year","title":"Cell founded","note":"Cell Press (Elsevier)","from":"cell","refs":[]},{"group":"journal","date":"1974","precision":"year","title":"Gan to kagaku ryoho. Cancer & chemotherapy founded","note":"Gan To Kagaku Ryohosha","from":"gan-to-kagaku-ryoho","refs":[]},{"group":"journal","date":"1974","precision":"year","title":"Radiation and environmental biophysics founded","note":"Springer (Springer-Verlag)","from":"radiation-and-environmental-biophysics","refs":[]},{"group":"journal","date":"1974","precision":"year","title":"Seminars in oncology founded","note":"Elsevier (W. B. Saunders)","from":"seminars-in-oncology","refs":[]},{"group":"paper","date":"1974","precision":"year","title":"Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice","note":"Stutman O. Science.","from":"paper-stutman-science","refs":[]}]},"route":"/years/1974/","neighbours":{"year":[{"id":"1973","kind":"year","name":"1973 in oncology","route":"/years/1973/"},{"id":"1975","kind":"year","name":"1975 in oncology","route":"/years/1975/"}]}}