{"entity":{"id":"1975","kind":"year","name":"1975 in oncology","aka":["1975"],"tldr":"Everything OnCo dates to 1975: 17 entries, 8 landmarks, 3 journals founded, 2 papers listed on people's pages and 2 technologies. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.","summary":"17 dated entries in OnCo fall in 1975: 8 landmarks, 3 journals founded, 2 papers listed on people's pages, 2 technologies, 1 approval and 1 paper.\n\nOf those, 17 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.\n\nEverything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.","asOf":"2026-09-25","links":[],"tags":[],"related":["1974","1976"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Generated from every dated field in the corpus, not written by hand. The groups and the fields behind them are listed in src/lib/year-groups.ts; the reader is src/lib/years.ts."],"year":1975,"events":[{"group":"approval","date":"1975","precision":"year","title":"Dacarbazine approved in US","note":"Metastatic malignant melanoma; Hodgkin disease (second line, combination)","from":"dacarbazine","refs":[]},{"group":"history","date":"1975","precision":"year","title":"ABVD introduced (Bonadonna); becomes global standard by the 1990s","note":"Hodgkin lymphoma","from":"hodgkin-lymphoma","refs":["doxorubicin"]},{"group":"history","date":"1975","precision":"year","title":"ABVD introduced in Milan and later shown superior to MOPP","note":"Advanced-stage classical Hodgkin lymphoma (stage III to IV)","from":"advanced-stage-classical-hodgkin-lymphoma","refs":["abvd-beacopp","doxorubicin"]},{"group":"history","date":"1975","precision":"year","title":"Bismuth and Corlette classify perihilar tumours by ductal extension","note":"Extrahepatic cholangiocarcinoma (perihilar and distal)","from":"extrahepatic-cholangiocarcinoma","refs":[]},{"group":"history","date":"1975","precision":"year","title":"Bonadonna introduces ABVD in Milan","note":"Early-stage classical Hodgkin lymphoma (stage I to II)","from":"early-stage-classical-hodgkin-lymphoma","refs":["abvd-beacopp","doxorubicin"]},{"group":"history","date":"1975","precision":"year","title":"Dacarbazine approved: about one in ten tumours respond","note":"Advanced melanoma (unresectable stage III and stage IV)","from":"advanced-melanoma","refs":["dacarbazine"]},{"group":"history","date":"1975","precision":"year","title":"Dacarbazine: ~10% response, standard for 35 years","note":"Melanoma","from":"melanoma","refs":[]},{"group":"history","date":"1975","precision":"year","title":"Mycosis fungoides staging (TNMB)","note":"Peripheral T-cell lymphomas (including cutaneous T-cell lymphoma)","from":"peripheral-t-cell-lymphoma","refs":[]},{"group":"history","date":"1975","precision":"year","title":"Rai staging system","note":"Chronic lymphocytic leukaemia. Clinical staging by lymphocytosis, nodes, organomegaly, cytopenias; Binet system follows in 1981.","from":"cll","refs":[]},{"group":"journal","date":"1975","precision":"year","title":"Cancer letters founded","note":"Elsevier","from":"cancer-letters","refs":[]},{"group":"journal","date":"1975","precision":"year","title":"European Urology founded","note":"Elsevier","from":"european-urology","refs":[]},{"group":"journal","date":"1975","precision":"year","title":"International Journal of Radiation Oncology, Biology, Physics founded","note":"Elsevier","from":"ijrobp","refs":[]},{"group":"paper","date":"1975","precision":"year","title":"Normal genetically mosaic mice produced from malignant teratocarcinoma cells","note":"Mintz B, Illmensee K. Proceedings of the National Academy of Sciences.","from":"paper-mintz-proc-natl-acad-sci-u-s-a","refs":[]},{"group":"person-paper","date":"1975","precision":"year","title":"\"Natural\" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells","note":"European Journal of Immunology","from":"rolf-kiessling","refs":[]},{"group":"person-paper","date":"1975","precision":"year","title":"Genetic control of cell size at cell division in yeast","note":"Nature","from":"paul-nurse","refs":[]},{"group":"technology","date":"1975","precision":"year","title":"PET (positron emission tomography)","note":"First use in humans or first approval, as the technology record states it.","from":"pet","refs":[]},{"group":"technology","date":"1975","precision":"year","title":"The four Rs and accelerated repopulation","note":"First use in humans or first approval, as the technology record states it.","from":"fractionation-repopulation-models","refs":[]}]},"route":"/years/1975/","neighbours":{"year":[{"id":"1974","kind":"year","name":"1974 in oncology","route":"/years/1974/"},{"id":"1976","kind":"year","name":"1976 in oncology","route":"/years/1976/"}]}}