{"entity":{"id":"1980","kind":"year","name":"1980 in oncology","aka":["1980"],"tldr":"Everything OnCo dates to 1980: 22 entries, 9 landmarks, 9 technologies, 2 companies founded and 1 approval. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.","summary":"22 dated entries in OnCo fall in 1980: 9 landmarks, 9 technologies, 2 companies founded, 1 approval and 1 journal founded.\n\nOf those, 22 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.\n\nEverything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.","asOf":"2026-09-25","links":[],"tags":[],"related":["1979","1981"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Generated from every dated field in the corpus, not written by hand. The groups and the fields behind them are listed in src/lib/year-groups.ts; the reader is src/lib/years.ts."],"year":1980,"events":[{"group":"approval","date":"1980","precision":"year","title":"Aminoglutethimide approved in US","note":"Cushing's syndrome (used off label as medical adrenalectomy in breast and prostate cancer)","from":"aminoglutethimide","refs":[]},{"group":"company","date":"1980","precision":"year","title":"Atlas Venture founded","note":"Cambridge, MA","from":"atlas-venture","refs":[]},{"group":"company","date":"1980","precision":"year","title":"IGEA founded","note":"Carpi, Modena","from":"igea","refs":[]},{"group":"history","date":"1980","precision":"year","title":"Blast crisis defined; median survival months with chemotherapy","note":"Chronic myeloid leukaemia, accelerated and blast phase","from":"cml-advanced-phase","refs":["blasts"]},{"group":"history","date":"1980","precision":"year","title":"Cisplatin and doxorubicin shown active; survival rises from ~30% to ~70%","note":"Hepatoblastoma","from":"hepatoblastoma","refs":["cisplatin","doxorubicin"]},{"group":"history","date":"1980","precision":"year","title":"Cisplatin-based chemotherapy cures young men with midline poorly differentiated carcinoma, defining the first favourable subset","note":"Cancer of unknown primary, favourable subsets","from":"cup-favourable-subsets","refs":["cisplatin"]},{"group":"history","date":"1980","precision":"year","title":"Cisplatin/5-FU chemoradiation defined (RTOG 85-01 reported 1992)","note":"Oesophageal cancer. Definitive chemoradiation shown superior to radiation alone; 5-year OS 26% vs 0%.","from":"esophageal","refs":["imrt-igrt","platinum"]},{"group":"history","date":"1980","precision":"year","title":"EBV linked to PTLD","note":"Post-transplant lymphoproliferative disorder (PTLD). Hanto and colleagues show EBV in lymphoproliferations of transplant recipients and regression with reduced immunosuppression.","from":"post-transplant-lymphoproliferative-disorder","refs":[]},{"group":"history","date":"1980","precision":"year","title":"High-dose methotrexate shown active in PCNSL","note":"Primary CNS lymphoma","from":"primary-cns-lymphoma","refs":["methotrexate"]},{"group":"history","date":"1980","precision":"year","title":"Kyle and Greipp define smouldering multiple myeloma","note":"Smouldering multiple myeloma","from":"smouldering-myeloma","refs":["smoldering-myeloma"]},{"group":"history","date":"1980","precision":"year","title":"Limb-salvage surgery shown equivalent to amputation (Rosenberg, NCI)","note":"Sarcomas (soft tissue, bone, GIST)","from":"sarcoma","refs":["limb-salvage-surgery"]},{"group":"history","date":"1980","precision":"year","title":"Mediastinal large B-cell lymphoma of thymic origin first described as a distinct clinical entity","note":"Primary mediastinal (thymic) large B-cell lymphoma","from":"primary-mediastinal-b-cell-lymphoma","refs":[]},{"group":"journal","date":"1980","precision":"year","title":"Carcinogenesis founded","note":"Oxford University Press","from":"carcinogenesis","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"Endoscopic ultrasound and EBUS systems","note":"First use in humans or first approval, as the technology record states it.","from":"endoscopic-ultrasound-systems","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"Generic sterile injectables (the 2023 platinum shortage)","note":"First use in humans or first approval, as the technology record states it.","from":"sterile-injectable-generics-manufacturing","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"High-dose-rate brachytherapy","note":"First use in humans or first approval, as the technology record states it.","from":"hdr-brachytherapy","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"Hyperthermia systems (BSD-2000, EHY-2000, superficial and interstitial applicators)","note":"First use in humans or first approval, as the technology record states it.","from":"hyperthermia-systems","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"Limb-salvage surgery and endoprosthetic reconstruction","note":"First use in humans or first approval, as the technology record states it.","from":"limb-salvage-surgery","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"Low-dose-rate seed brachytherapy","note":"First use in humans or first approval, as the technology record states it.","from":"ldr-seed-brachytherapy","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"Oncology information and record-and-verify systems (ARIA, MOSAIQ)","note":"First use in humans or first approval, as the technology record states it.","from":"oncology-information-systems","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"The linear-quadratic model and fractionation","note":"First use in humans or first approval, as the technology record states it.","from":"linear-quadratic-model","refs":[]},{"group":"technology","date":"1980","precision":"year","title":"Transarterial chemoembolisation (TACE)","note":"First use in humans or first approval, as the technology record states it.","from":"tace","refs":[]}]},"route":"/years/1980/","neighbours":{"year":[{"id":"1979","kind":"year","name":"1979 in oncology","route":"/years/1979/"},{"id":"1981","kind":"year","name":"1981 in oncology","route":"/years/1981/"}]}}