{"entity":{"id":"1982","kind":"year","name":"1982 in oncology","aka":["1982"],"tldr":"Everything OnCo dates to 1982: 27 entries, 16 landmarks, 5 journals founded, 2 approvals and 2 papers listed on people's pages. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.","summary":"27 dated entries in OnCo fall in 1982: 16 landmarks, 5 journals founded, 2 approvals, 2 papers listed on people's pages, 1 company founded and 1 paper.\n\nOf those, 27 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.\n\nEverything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.","asOf":"2026-09-25","links":[],"tags":[],"related":["1981","1983"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Generated from every dated field in the corpus, not written by hand. The groups and the fields behind them are listed in src/lib/year-groups.ts; the reader is src/lib/years.ts."],"year":1982,"events":[{"group":"approval","date":"1982","precision":"year","title":"Isotretinoin approved in US","note":"Severe recalcitrant nodular acne (use in high-risk neuroblastoma is off-label but standard)","from":"isotretinoin","refs":[]},{"group":"approval","date":"1982","precision":"year","title":"Streptozocin approved in US","note":"Metastatic islet cell carcinoma of the pancreas","from":"streptozocin","refs":[]},{"group":"company","date":"1982","precision":"year","title":"GIMEMA founded","note":"Rome","from":"gimema","refs":[]},{"group":"history","date":"1982","precision":"year","title":"Adjuvant radiotherapy improves local control after limb-sparing surgery (NCI randomised trial)","note":"Sarcomas (soft tissue, bone, GIST)","from":"sarcoma","refs":["imrt-igrt"]},{"group":"history","date":"1982","precision":"year","title":"FAB classification includes CMML within MDS","note":"Chronic myelomonocytic leukaemia and MDS/MPN overlap neoplasms","from":"cmml","refs":[]},{"group":"history","date":"1982","precision":"year","title":"FAB classification of MDS","note":"Myelodysplastic syndromes / neoplasms (MDS). Bennett and colleagues define refractory anaemia, RARS, RAEB, RAEB-T and CMML.","from":"mds","refs":[]},{"group":"history","date":"1982","precision":"year","title":"Heald describes total mesorectal excision, cutting local recurrence to under 10 percent","note":"Rectal cancer","from":"rectal-cancer","refs":["total-mesorectal-excision"]},{"group":"history","date":"1982","precision":"year","title":"Hendrickson describes uterine papillary serous carcinoma as a distinct aggressive type","note":"p53-abnormal endometrial cancer, including uterine serous carcinoma","from":"endometrial-p53-abnormal","refs":[]},{"group":"history","date":"1982","precision":"year","title":"KRAS identified as a human oncogene","note":"Pancreatic ductal adenocarcinoma. Within a decade shown to be mutated in ~90% of pancreatic cancers.","from":"pancreatic","refs":["kras"]},{"group":"history","date":"1982","precision":"year","title":"KRAS identified as a human oncogene","note":"KRAS G12C-mutant colorectal cancer","from":"kras-g12c-colorectal","refs":["kras"]},{"group":"history","date":"1982","precision":"year","title":"KRAS identified as a human oncogene in lung cancer cell lines","note":"KRAS G12C-mutant non-small-cell lung cancer","from":"kras-g12c-nsclc","refs":["kras","oncogene"]},{"group":"history","date":"1982","precision":"year","title":"Lymphoma recognised as an AIDS-defining illness","note":"HIV-associated (AIDS-related) lymphomas. Aggressive B-cell lymphoma in young men with AIDS reported; added to the CDC case definition in 1985.","from":"hiv-associated-lymphoma","refs":[]},{"group":"history","date":"1982","precision":"year","title":"MYC mapped to the translocation breakpoint","note":"Burkitt lymphoma. Dalla-Favera and Taub show MYC is juxtaposed to the immunoglobulin heavy-chain locus.","from":"burkitt-lymphoma","refs":["myc"]},{"group":"history","date":"1982","precision":"year","title":"Ohhashi describes mucin-producing pancreatic tumours, later named IPMN","note":"Intraductal papillary mucinous neoplasm and other pancreatic cystic precursors","from":"ipmn-cystic-precursors","refs":["endoscopy"]},{"group":"history","date":"1982","precision":"year","title":"Rosenberg NCI trial: limb-sparing surgery plus radiotherapy equals amputation","note":"Soft tissue sarcoma of the extremity (localised and advanced)","from":"extremity-soft-tissue-sarcoma","refs":["limb-salvage-surgery"]},{"group":"history","date":"1982","precision":"year","title":"Streptozocin approved for metastatic islet cell carcinoma","note":"Pancreatic neuroendocrine tumours","from":"pancreatic-net","refs":["streptozocin"]},{"group":"history","date":"1982","precision":"year","title":"Total mesorectal excision described","note":"Colorectal cancer. Heald found cancer deposits in the mesorectum several centimetres below the tumour and removed the whole envelope instead of cutting through it; the first 50 cur...","from":"colorectal","refs":["total-mesorectal-excision"]},{"group":"history","date":"1982","precision":"year","title":"Weiss and Enzinger define epithelioid haemangioendothelioma","note":"Vascular tumours (angiosarcoma, epithelioid haemangioendothelioma, kaposiform haemangioendothelioma)","from":"vascular-tumours","refs":[]},{"group":"history","date":"1982","precision":"year","title":"Weiss and Enzinger describe epithelioid haemangioendothelioma","note":"Epithelioid haemangioendothelioma","from":"epithelioid-haemangioendothelioma","refs":[]},{"group":"journal","date":"1982","precision":"year","title":"American journal of clinical oncology founded","note":"Lippincott Williams & Wilkins (Wolters Kluwer)","from":"american-journal-of-clinical-oncology","refs":[]},{"group":"journal","date":"1982","precision":"year","title":"Cancer immunology, immunotherapy founded","note":"Springer","from":"cancer-immunology-immunotherapy","refs":[]},{"group":"journal","date":"1982","precision":"year","title":"Cancer metastasis reviews founded","note":"Springer","from":"cancer-metastasis-reviews","refs":[]},{"group":"journal","date":"1982","precision":"year","title":"Journal of experimental & clinical cancer research founded","note":"BMC (Springer Nature)","from":"journal-of-experimental-and-clinical-cancer-research","refs":[]},{"group":"journal","date":"1982","precision":"year","title":"Journal of the Egyptian National Cancer Institute founded","note":"SpringerOpen (Springer Nature)","from":"journal-of-the-egyptian-national-cancer-institute","refs":[]},{"group":"paper","date":"1982","precision":"year","title":"The mesorectum in rectal cancer surgery: the clue to pelvic recurrence?","note":"Heald RJ, Husband EM, Ryall RD. British Journal of Surgery.","from":"paper-heald-mesorectum-rectal-cancer-surgery-br-j-surg-1982","refs":[]},{"group":"person-paper","date":"1982","precision":"year","title":"The National Cancer Chemotherapy Program","note":"Science","from":"emil-frei","refs":[]},{"group":"person-paper","date":"1982","precision":"year","title":"Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody","note":"New England Journal of Medicine","from":"ronald-levy","refs":[]}]},"route":"/years/1982/","neighbours":{"year":[{"id":"1981","kind":"year","name":"1981 in oncology","route":"/years/1981/"},{"id":"1983","kind":"year","name":"1983 in oncology","route":"/years/1983/"}]}}