{"entity":{"id":"1989","kind":"year","name":"1989 in oncology","aka":["1989"],"tldr":"Everything OnCo dates to 1989: 30 entries, 6 approvals, 6 journals founded, 5 landmarks and 5 papers listed on people's pages. Each line links to the record it was read from, so the year is a view of the corpus rather than a second copy of it.","summary":"30 dated entries in OnCo fall in 1989: 6 approvals, 6 journals founded, 5 landmarks, 5 papers listed on people's pages, 4 papers, 3 companies founded and 1 regulatory event.\n\nOf those, 1 to the day and 29 to the year only. Most of the corpus dates a fact to the year, because that is what the source it was read from gives; regulatory events and the readout calendar are the parts that carry a full date.\n\nEverything on this page is generated from the other records. It holds no fact of its own, and it changes when they do.","asOf":"2026-09-25","links":[],"tags":[],"related":["1988","1990"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Generated from every dated field in the corpus, not written by hand. The groups and the fields behind them are listed in src/lib/year-groups.ts; the reader is src/lib/years.ts."],"year":1989,"events":[{"group":"approval","date":"1989","precision":"year","title":"Carboplatin approved in US","note":"Ovarian cancer (now broad use)","from":"carboplatin","refs":[]},{"group":"approval","date":"1989","precision":"year","title":"Epoetin alfa approved in US","note":"Anaemia of chronic kidney disease","from":"epoetin-alfa","refs":[]},{"group":"approval","date":"1989","precision":"year","title":"Flutamide approved in US","note":"Locally advanced (B2 to C) and metastatic (D2) prostate cancer in combination with an LHRH agonist","from":"flutamide","refs":[]},{"group":"approval","date":"1989","precision":"year","title":"Goserelin / leuprolide (ovarian function suppression) approved in US","note":"Advanced breast cancer (goserelin); prostate cancer","from":"goserelin","refs":[]},{"group":"approval","date":"1989","precision":"year","title":"Leuprolide (leuprorelin) and GnRH agonists approved in US","note":"Depot formulation (Lupron Depot)","from":"leuprolide","refs":[]},{"group":"approval","date":"1989","precision":"year","title":"Vinorelbine approved in EU","note":"NSCLC, metastatic breast cancer","from":"vinorelbine","refs":[]},{"group":"company","date":"1989","precision":"year","title":"Idera Pharmaceuticals founded","note":"Cambridge, MA","from":"idera-pharmaceuticals","refs":[]},{"group":"company","date":"1989","precision":"year","title":"Ionis Pharmaceuticals founded","note":"Carlsbad, CA","from":"ionis","refs":[]},{"group":"company","date":"1989","precision":"year","title":"TROG Cancer Research founded","note":"Newcastle, NSW","from":"trog","refs":[]},{"group":"history","date":"1989","precision":"year","title":"BEP ×3 sufficient for good-risk disease (Einhorn)","note":"Testicular germ cell tumours","from":"testicular","refs":[]},{"group":"history","date":"1989","precision":"year","title":"Carboplatin approved; platinum-free interval emerges as the guide to re-treatment","note":"Platinum-sensitive ovarian cancer","from":"platinum-sensitive-ovarian-cancer","refs":["carboplatin"]},{"group":"history","date":"1989","precision":"year","title":"CCG-943: chemotherapy adds to radiotherapy in childhood high-grade glioma","note":"Paediatric high-grade glioma (excluding diffuse midline glioma). Sposto and colleagues, the first randomised evidence for adjuvant chemotherapy in children.","from":"paediatric-high-grade-glioma","refs":[]},{"group":"history","date":"1989","precision":"year","title":"HHV-8 and EBV linked to AIDS lymphomas","note":"HIV-associated (AIDS-related) lymphomas. EBV in CNS lymphoma; HHV-8 (KSHV) identified in 1994 and linked to primary effusion lymphoma in 1995.","from":"hiv-associated-lymphoma","refs":["ebv-term"]},{"group":"history","date":"1989","precision":"year","title":"US EPA asbestos ban partly overturned (1991); many countries ban asbestos over the following decades","note":"Mesothelioma","from":"mesothelioma","refs":[]},{"group":"journal","date":"1989","precision":"year","title":"Clinical oncology founded","note":"Elsevier","from":"clinical-oncology-rcr","refs":[]},{"group":"journal","date":"1989","precision":"year","title":"Critical reviews in oncogenesis founded","note":"Begell House","from":"critical-reviews-in-oncogenesis","refs":[]},{"group":"journal","date":"1989","precision":"year","title":"Current opinion in oncology founded","note":"Lippincott Williams & Wilkins (Wolters Kluwer)","from":"current-opinion-in-oncology","refs":[]},{"group":"journal","date":"1989","precision":"year","title":"Genes, chromosomes & cancer founded","note":"Wiley","from":"genes-chromosomes-and-cancer","refs":[]},{"group":"journal","date":"1989","precision":"year","title":"Head & neck founded","note":"Wiley","from":"head-and-neck-journal","refs":[]},{"group":"journal","date":"1989","precision":"year","title":"Leukemia & lymphoma founded","note":"Taylor & Francis","from":"leukemia-and-lymphoma","refs":[]},{"group":"paper","date":"1989","precision":"year","title":"Carboplatin dosage: prospective evaluation of a simple formula based on renal function","note":"Calvert AH, Newell DR, Gumbrell LA, et al. Journal of Clinical Oncology.","from":"paper-calvert-j-clin-oncol","refs":[]},{"group":"paper","date":"1989","precision":"year","title":"Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity","note":"Gross G, Waks T, Eshhar Z. Proceedings of the National Academy of Sciences.","from":"paper-gross-eshhar-chimeric-receptor-pnas-1989","refs":[]},{"group":"paper","date":"1989","precision":"year","title":"Slamon 1989: HER2/neu in human breast and ovarian cancer","note":"Slamon DJ, Godolphin W, Jones LA, et al. Science.","from":"paper-slamon-her2-breast-ovarian-science-1989","refs":[]},{"group":"paper","date":"1989","precision":"year","title":"The distribution of secondary growths in cancer of the breast. 1889","note":"Paget S. Cancer metastasis reviews.","from":"paper-paget-cancer-metastasis-rev","refs":[]},{"group":"person-paper","date":"1989","precision":"year","title":"Bone marrow autotransplantation for solid tumors--prospects.","note":"Journal of Clinical Oncology","from":"emil-frei","refs":[]},{"group":"person-paper","date":"1989","precision":"year","title":"Induction of angiogenesis during the transition from hyperplasia to neoplasia","note":"Nature","from":"judah-folkman","refs":[]},{"group":"person-paper","date":"1989","precision":"year","title":"The Purine Path to Chemotherapy","note":"Science","from":"gertrude-elion","refs":[]},{"group":"person-paper","date":"1989","precision":"year","title":"The Purine Path to Chemotherapy (Nobel Lecture)","note":"Angewandte Chemie International Edition in English","from":"gertrude-elion","refs":[]},{"group":"person-paper","date":"1989","precision":"year","title":"Tumor necrosis factor: still a promising agent.","note":"Journal of Clinical Oncology","from":"emil-frei","refs":[]},{"group":"regulatory","date":"1989-03-03","precision":"day","title":"Carboplatin: approval (US)","note":"Ovarian cancer","from":"carboplatin","refs":[]}]},"route":"/years/1989/","neighbours":{"year":[{"id":"1988","kind":"year","name":"1988 in oncology","route":"/years/1988/"},{"id":"1990","kind":"year","name":"1990 in oncology","route":"/years/1990/"}]}}