{"entity":{"id":"4sc","kind":"company","name":"4SC","aka":["4SC AG","4Sc AG"],"tldr":"4SC is a listed German biotechnology company founded in 1997 in Planegg-Martinsried, near Munich. It applied to the EMA for its HDAC inhibitor resminostat (Kinselby) in advanced mycosis fungoides and Sézary syndrome and received a negative opinion in May 2025.","summary":"4SC is a public company based in Martinsried, Germany, founded in 1997 (Wikidata Q238181, which also gives its website). The EMA product page for Kinselby (resminostat, orphan designation) names 4Sc AG as the marketing authorisation applicant; the CHMP adopted its opinion on 22 May 2025 and the opinion status is negative, so the product is not authorised. It sponsors no trial recorded in OnCo.","asOf":"2026-09-22","links":[{"label":"Official website","url":"https://www.4sc.com/"},{"label":"Wikidata Q238181","url":"https://www.wikidata.org/wiki/Q238181"},{"label":"EMA: Kinselby (EPAR)","url":"https://www.ema.europa.eu/en/medicines/human/EPAR/kinselby"}],"tags":["ctgov-sponsor","wave5-sponsor"],"related":[],"cancers":["cutaneous-t-cell-lymphoma"],"sections":[],"technologies":["epigenetic-drugs"],"targets":["hdac"],"drugs":["resminostat"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo content wave 5 (Wikidata, ClinicalTrials.gov v2, corpus trial records)","editedOn":"2026-09-22"},"hq":"Planegg-Martinsried","country":"DE","companyType":"biotech","website":"https://www.4sc.com/","founded":1997,"stage":"public","investors":[],"funding":[]},"route":"/companies/4sc/","neighbours":{"cancer":[{"id":"cutaneous-t-cell-lymphoma","kind":"cancer","name":"Cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)","route":"/cancers/cutaneous-t-cell-lymphoma/"}],"technology":[{"id":"epigenetic-drugs","kind":"technology","name":"Epigenetic drugs (HDAC, DNMT, EZH2, IDH, menin, BET)","route":"/technologies/epigenetic-drugs/"}],"target":[{"id":"hdac","kind":"target","name":"Histone deacetylases (HDAC)","route":"/targets/hdac/"}],"drug":[{"id":"resminostat","kind":"drug","name":"Resminostat","route":"/drugs/resminostat/"}]}}