{"entity":{"id":"714-x","kind":"technology","name":"714-X","aka":["714X"],"tldr":"714-X is a camphor-based injection made in Quebec and promoted as a way to restore the immune system against cancer. No study of it has been published in a peer-reviewed journal, and the FDA has banned its import into the United States.","summary":"714-X was developed in the 1960s in a private laboratory in Quebec, Canada, where it is still produced. It is promoted as a sterile solution of chemically modified camphor with nitrates and ammonium, injected into the lymphatics of the groin daily for 21 days in repeated cycles, with inhaled treatment added for head and neck or lung cancer. Memorial Sloan Kettering's About Herbs page states that 714-X has not been evaluated for any of its claims and that it is illegal in the United States and available in Canada only through compassionate use. The NCI PDQ summary, no longer being updated, states that no study of 714-X has been published in a peer-reviewed scientific journal to show that it is safe or effective, and that the FDA has placed an import ban on it. Reported side effects are redness, inflammation and soreness at the injection site. According to the manufacturer, its effect may be reduced by vitamin B12, vitamin E and shark or bovine cartilage, products often sold to the same readers.","status":"negative","asOf":"2026-11-04","links":[{"label":"MSK About Herbs: 714X (page last updated 6 January 2022)","url":"https://www.mskcc.org/cancer-care/integrative-medicine/herbs/714x"},{"label":"NCI PDQ: 714-X","url":"https://www.cancer.gov/about-cancer/treatment/cam/hp/714-x-pdq"}],"tags":["complementary","supportive-care","evidence:insufficient"],"related":["cancell-protocel","ukrain"],"cancers":[],"sections":["supportive-care"],"technologies":["alternative-medicine-instead-of-treatment","shark-cartilage"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["unproven-diet-claims"],"trials":[],"people":[],"bottlenecks":["b-misinformation"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"principle":"Claimed to supply nitrogen to cancer cells and so release the immune system; no evidence supports the mechanism.","strengths":["None established"],"limitations":["No peer-reviewed study of safety or efficacy","Import banned in the United States","Requires daily injections into lymph nodes"]},"route":"/technologies/714-x/","neighbours":{"technology":[{"id":"alternative-medicine-instead-of-treatment","kind":"technology","name":"Alternative medicine used instead of standard treatment","route":"/technologies/alternative-medicine-instead-of-treatment/"},{"id":"cancell-protocel","kind":"technology","name":"Cancell, Cantron and Protocel","route":"/technologies/cancell-protocel/"},{"id":"shark-cartilage","kind":"technology","name":"Shark cartilage (AE-941, Neovastat)","route":"/technologies/shark-cartilage/"},{"id":"ukrain","kind":"technology","name":"Ukrain (NSC 631570)","route":"/technologies/ukrain/"}],"section":[{"id":"supportive-care","kind":"section","name":"Supportive Care & Survivorship","route":"/fronts/supportive-care/"}],"term":[{"id":"unproven-diet-claims","kind":"term","name":"Unproven diet claims (alkaline, juice, 'anti-cancer' diets)","route":"/terms/unproven-diet-claims/"}],"bottleneck":[{"id":"b-misinformation","kind":"bottleneck","name":"Misinformation and unproven therapies","route":"/bottlenecks/b-misinformation/"}]}}