{"entity":{"id":"abbisko","kind":"company","name":"Abbisko Therapeutics","aka":["Abbisko Therapeutics Co, Ltd","和誉生物"],"tldr":"Abbisko is a Shanghai biotech listed in Hong Kong whose CSF-1R inhibitor pimicotinib met its phase 3 endpoint in tenosynovial giant cell tumour, a rare joint tumour, and is licensed to Merck KGaA.","summary":"Abbisko Therapeutics, based in Shanghai and listed in Hong Kong, develops small-molecule kinase inhibitors. Its lead drug pimicotinib (ABSK021), a selective CSF-1R inhibitor, met the primary endpoint of the phase 3 MANEUVER trial in tenosynovial giant cell tumour and is partnered with Merck KGaA outside China; FGFR4 and pan-FGFR inhibitors follow in liver and urothelial cancer. Its trials are registered on ClinicalTrials.gov under Abbisko as lead sponsor.","asOf":"2026-09-11","links":[{"label":"Official website","url":"https://www.abbisko.com"},{"label":"ClinicalTrials.gov: trials led by Abbisko Therapeutics Co, Ltd","url":"https://clinicaltrials.gov/search?lead=Abbisko%20Therapeutics%20Co%2C%20Ltd"},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q140045781"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["tenosynovial-giant-cell-tumour","hcc"],"sections":[],"technologies":[],"targets":["csf1r"],"drugs":[],"companies":["merck-kgaa"],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Shanghai","country":"CN","companyType":"biotech","website":"https://www.abbisko.com","stage":"public","investors":[],"funding":[]},"route":"/companies/abbisko/","neighbours":{"cancer":[{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"tenosynovial-giant-cell-tumour","kind":"cancer","name":"Tenosynovial giant cell tumour (TGCT)","route":"/cancers/tenosynovial-giant-cell-tumour/"}],"target":[{"id":"csf1r","kind":"target","name":"CSF1R","route":"/targets/csf1r/"}],"company":[{"id":"merck-kgaa","kind":"company","name":"Merck KGaA (EMD Serono)","route":"/companies/merck-kgaa/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}