{"entity":{"id":"acacia-pharma","kind":"company","name":"Acacia Pharma","aka":["Acacia Pharma Ltd","Acacia Pharma Group"],"tldr":"Acacia Pharma was a Cambridge company that repurposed the old antipsychotic amisulpride, at low dose, to prevent and treat nausea and vomiting after surgery and chemotherapy; it was bought by Eagle Pharmaceuticals in 2022.","summary":"Acacia Pharma, founded in 2007 in Cambridge, England, developed intravenous low-dose amisulpride (Barhemsys) for postoperative nausea and vomiting, approved by the FDA in 2020, and tested the same drug (APD403) in phase 3 for chemotherapy-induced nausea and vomiting. Eagle Pharmaceuticals acquired the company in 2022. Its trials remain on ClinicalTrials.gov under Acacia as lead sponsor.","asOf":"2026-09-11","links":[{"label":"Official website","url":"http://www.acaciapharma.com"},{"label":"ClinicalTrials.gov: trials led by Acacia Pharma Ltd","url":"https://clinicaltrials.gov/search?lead=Acacia%20Pharma%20Ltd"},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q30268747"}],"tags":["ctgov-sponsor"],"related":[],"cancers":[],"sections":["supportive-care"],"technologies":["antiemetic-therapy"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Cambridge","country":"GB","companyType":"pharma","website":"http://www.acaciapharma.com","founded":2007,"stage":"acquired","investors":[],"funding":[]},"route":"/companies/acacia-pharma/","neighbours":{"section":[{"id":"supportive-care","kind":"section","name":"Supportive Care & Survivorship","route":"/fronts/supportive-care/"}],"technology":[{"id":"antiemetic-therapy","kind":"technology","name":"Antiemetics for chemotherapy-induced nausea and vomiting","route":"/technologies/antiemetic-therapy/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}