{"entity":{"id":"acomhal-research","kind":"company","name":"Acomhal Research","aka":["Acomhal Research, Inc."],"tldr":"Acomhal Research is a Virginia company developing a peptide drug aimed at the treatment-resistant cells that let cancers such as glioblastoma grow back after treatment.","summary":"Acomhal Research, Inc. develops a patented mimetic peptide derived from connexin 43 (Cx43) as an add-on therapy against chemotherapy-resistant cancer cells, with programmes listed in glioblastoma, breast, colon, pancreatic and lung cancer and melanoma. The company reports that the peptide eliminated chemotherapy-resistant glioblastoma cells, including glioma stem cells, in laboratory and animal studies. A 2026 National Cancer Institute STTR award funds alphavirus vector-mediated expression of the Cx43 mimetic peptide, named JM2 in the award abstract, for glioblastoma.","asOf":"2026-11-04","links":[{"label":"Official website","url":"https://acomhal.com/"},{"label":"Glioblastoma programme","url":"https://acomhal.com/glioblastoma/"},{"label":"NIH RePORTER: award 1R41CA306619-01A1","url":"https://reporter.nih.gov/project-details/11409740"}],"tags":[],"related":[],"cancers":["glioblastoma"],"sections":["targeted-therapy"],"technologies":[],"targets":[],"drugs":["jm2"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Company website (home and glioblastoma pages) and the NIH RePORTER record read on 4 November 2026. The website does not name its peptide; the name JM2 is from the award abstract."],"hq":"Roanoke, VA","country":"US","companyType":"biotech","website":"https://acomhal.com/","stage":"startup","investors":[],"funding":[{"round":"Grant","year":2026,"amountUsd":400000,"source":"https://reporter.nih.gov/project-details/11409740","note":"NCI STTR (R41) award 1R41CA306619-01A1: Alphavirus vector-mediated expression of a connexin43 mimetic peptide in glioblastoma therapy"}]},"route":"/companies/acomhal-research/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"section":[{"id":"targeted-therapy","kind":"section","name":"Targeted Therapy","route":"/fronts/targeted-therapy/"}],"drug":[{"id":"jm2","kind":"drug","name":"JM2","route":"/drugs/jm2/"}]}}