{"entity":{"id":"acoxl","kind":"target","name":"ACOXL","aka":["acyl-CoA oxidase like","Acyl-coenzyme A oxidase-like protein","FLJ11042","ACOX4"],"tldr":"ACOXL (Acyl-coenzyme A oxidase-like protein) is an enzyme. In the public catalogues the evidence so far is association rather than a proven role. Tied to Leukaemia.","summary":"UniProt has no function text for Q9NUZ1; HGNC names it \"acyl-CoA oxidase like\".\n\n","asOf":"2026-09-23","links":[{"label":"HGNC HGNC:25621","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:25621"},{"label":"UniProt Q9NUZ1","url":"https://www.uniprot.org/uniprotkb/Q9NUZ1/entry"},{"label":"NCBI Gene 55289","url":"https://www.ncbi.nlm.nih.gov/gene/55289"},{"label":"Ensembl ENSG00000153093","url":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000153093"}],"tags":["cancer-genes-wave"],"related":["open-targets"],"cancers":["leukaemia"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier \"association-only\" is the strongest of those signals.","Prevalence not recorded: none of the sources gives a positivity rate."],"provenance":{"editedBy":"scripts/fetch-cancer-genes.ts (CIViC, Open Targets, IntOGen, HGNC, UniProt)","editedOn":"2026-09-23"},"symbol":"ACOXL","role":[],"evidenceTier":"association-only","sources":[{"label":"HGNC HGNC:25621","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:25621","note":"approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)"},{"label":"UniProt Q9NUZ1","url":"https://www.uniprot.org/uniprotkb/Q9NUZ1/entry","note":"protein name, function text, keywords and locations (REST API)"},{"label":"Open Targets ENSG00000153093","url":"https://platform.opentargets.org/target/ENSG00000153093/associations","note":"per-cancer scores at or above 0.5: leukaemia 0.51 (GraphQL API, CC0)"}],"hgnc":"HGNC:25621","ensembl":"ENSG00000153093","uniprot":"Q9NUZ1","entrez":"55289","biology":"UniProt has no function text for Q9NUZ1; HGNC names it \"acyl-CoA oxidase like\". Locus 2q13 (HGNC).","whereFound":["Leukaemia: Open Targets association 0.51 with leukaemia (MONDO_0005059)"],"targetClass":"enzyme","prevalence":[]},"route":"/targets/acoxl/","neighbours":{"collection":[{"id":"open-targets","kind":"collection","name":"Open Targets Platform","route":"/collections/open-targets/"}],"cancer":[{"id":"leukaemia","kind":"cancer","name":"Leukaemia (all types)","route":"/cancers/leukaemia/"}]}}