{"entity":{"id":"aeterna-zentaris","kind":"company","name":"Aeterna Zentaris","aka":["AEterna Zentaris","Aeterna Zentaris Inc.","Zentaris GmbH"],"tldr":"Aeterna Zentaris is a Frankfurt-based biotech whose oncology programmes, including the alkylphospholipid perifosine and the LHRH antagonist ozarelix, went through phase 3 trials it led; its approved product is a growth hormone deficiency test.","summary":"Aeterna Zentaris, headquartered in Frankfurt am Main and listed in Toronto and on Nasdaq, developed cancer drug candidates including perifosine (tested in phase 3 in multiple myeloma and colorectal cancer) and zoptarelin doxorubicin (a doxorubicin-LHRH conjugate tested in endometrial cancer), none of which reached approval. Its marketed product, macimorelin, is a diagnostic for adult growth hormone deficiency. It appears on ClinicalTrials.gov as lead sponsor of phase 3 cancer trials.","asOf":"2026-09-11","links":[{"label":"Official website","url":"https://www.aezsinc.com"},{"label":"ClinicalTrials.gov: trials led by AEterna Zentaris","url":"https://clinicaltrials.gov/search?lead=AEterna%20Zentaris"},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q30268820"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["multiple-myeloma","colorectal"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Frankfurt","country":"DE","companyType":"biotech","website":"https://www.aezsinc.com","founded":2001,"stage":"public","investors":[],"funding":[]},"route":"/companies/aeterna-zentaris/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"multiple-myeloma","kind":"cancer","name":"Multiple myeloma","route":"/cancers/multiple-myeloma/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}