{"entity":{"id":"ajcc-stage","kind":"term","name":"AJCC stage (TNM staging manual)","aka":["AJCC stage","AJCC staging","AJCC 8th edition","AJCC TNM","pathologic stage","clinical stage"],"tldr":"AJCC stage is the stage group (I to IV) assigned from the TNM manual published by the American Joint Committee on Cancer; it is the staging most clinical tables record.","summary":"Cancer staging determines how far a cancer has grown and spread, assigning a number from I to IV from tumour size, invasion, nodes and metastasis (Wikipedia). The American Joint Committee on Cancer, housed at the American College of Surgeons, publishes the TNM staging manual (currently the eighth edition, with a ninth edition rolling out by disease site) used in the United States and, jointly with the UICC, worldwide. Editions change the definitions, so a stage III in a 2005 cohort and in a 2020 cohort are not identical variables.","asOf":"2026-09-24","links":[{"label":"American Joint Committee on Cancer (American College of Surgeons)","url":"https://www.facs.org/quality-programs/cancer-programs/american-joint-committee-on-cancer/"},{"label":"Wikipedia: cancer staging","url":"https://en.wikipedia.org/wiki/Cancer_staging"}],"tags":["cansim-terms"],"related":["cancer-ai-vocabulary"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["tnm-staging","grade-vs-stage","clinical-covariates","staging-systems"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Listed in the CanSim terms map 1.0.0 (docs/onco/terms.json, generated 2026-09-24), CC BY 4.0, attribution: CanSim project, an open, public-data-first cancer foundation-model programme; CanSim page path /terms/ajcc-stage."],"provenance":{"editedBy":"OnCo CanSim terms wave (Wikipedia summaries, standards and project pages, GDC and FDA pages, Europe PMC)","editedOn":"2026-09-24","note":"CanSim terms map 1.0.0 (docs/onco/terms.json, generated 2026-09-24), CC BY 4.0, attribution: CanSim project, an open, public-data-first cancer foundation-model programme"},"category":"Pathology"},"route":"/terms/ajcc-stage/","neighbours":{"term":[{"id":"cancer-ai-vocabulary","kind":"term","name":"Cancer AI vocabulary (CanSim terms map)","route":"/terms/cancer-ai-vocabulary/"},{"id":"clinical-covariates","kind":"term","name":"Clinical covariates (age, stage, nodes, treatment flags)","route":"/terms/clinical-covariates/"},{"id":"staging-systems","kind":"term","name":"Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC)","route":"/terms/staging-systems/"},{"id":"grade-vs-stage","kind":"term","name":"Grade versus stage","route":"/terms/grade-vs-stage/"},{"id":"tnm-staging","kind":"term","name":"TNM staging","route":"/terms/tnm-staging/"}]}}