{"entity":{"id":"anthony-nichols","kind":"person","name":"Anthony C. Nichols","aka":[],"tldr":"Canadian surgeon who led ORATOR, the first randomised trial to compare robotic surgery with radiotherapy for early throat cancer, which found swallowing was slightly better after radiotherapy.","summary":"Anthony Nichols is a head and neck surgeon at Western University and London Health Sciences Centre in London, Ontario. He was first author of the 2019 Lancet Oncology report of ORATOR, the phase 2 trial that randomised patients with early oropharyngeal cancer to radiotherapy or transoral robotic surgery and found swallowing-related quality of life was modestly better after radiotherapy at one year. He also led ORATOR2 in HPV-positive disease.","asOf":"2026-09-18","links":[],"tags":["head-and-neck","surgery","trialist"],"related":[],"cancers":["hpv-positive-oropharyngeal-cancer","oropharyngeal-cancer","head-and-neck"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["lhsc-verspeeten"],"pathways":[],"terms":[],"trials":["orator"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Head and neck surgeon, Western University and London Health Sciences Centre, Ontario","institutionId":"lhsc-verspeeten","specialisms":["Oropharyngeal cancer","Transoral robotic surgery","Randomised surgical trials"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Nichols%5BAuthor%5D"}],"papers":[],"orcid":"0000-0002-0760-980X"},"route":"/people/anthony-nichols/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"hpv-positive-oropharyngeal-cancer","kind":"cancer","name":"HPV-positive oropharyngeal cancer","route":"/cancers/hpv-positive-oropharyngeal-cancer/"},{"id":"oropharyngeal-cancer","kind":"cancer","name":"Oropharyngeal cancer (tonsil and base of tongue)","route":"/cancers/oropharyngeal-cancer/"}],"institution":[{"id":"lhsc-verspeeten","kind":"institution","name":"Verspeeten Family Cancer Centre, London Health Sciences Centre","route":"/institutions/lhsc-verspeeten/"}],"trial":[{"id":"orator","kind":"trial","name":"ORATOR","route":"/trials/orator/"}]}}