{"entity":{"id":"antoine-italiano","kind":"person","name":"Antoine Italiano","aka":[],"tldr":"Bordeaux oncologist who led CABONE, the trial that showed cabozantinib shrinks or stabilises osteosarcoma and Ewing sarcoma after standard treatment has failed.","summary":"Antoine Italiano leads early-phase trials and the sarcoma unit at Institut Bergonié in Bordeaux. He was first author of the 2020 Lancet Oncology report of CABONE, the French Sarcoma Group phase 2 trial in which cabozantinib produced responses and prolonged disease control in advanced Ewing sarcoma and osteosarcoma. He also leads the PROFILER and other molecular profiling programmes in France.","asOf":"2026-09-18","links":[],"tags":["sarcoma","early-phase","trialist"],"related":[],"cancers":["osteosarcoma","ewing-sarcoma","sarcoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["institut-bergonie"],"pathways":[],"terms":[],"trials":["cabone"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Head of Early-Phase Trials and Sarcoma Unit, Institut Bergonié, Bordeaux","institutionId":"institut-bergonie","specialisms":["Sarcoma","Early-phase trials","Precision oncology"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Italiano%5BAuthor%5D"}],"papers":[]},"route":"/people/antoine-italiano/","neighbours":{"cancer":[{"id":"ewing-sarcoma","kind":"cancer","name":"Ewing sarcoma","route":"/cancers/ewing-sarcoma/"},{"id":"osteosarcoma","kind":"cancer","name":"Osteosarcoma","route":"/cancers/osteosarcoma/"},{"id":"sarcoma","kind":"cancer","name":"Sarcomas (soft tissue, bone, GIST)","route":"/cancers/sarcoma/"}],"institution":[{"id":"institut-bergonie","kind":"institution","name":"Institut Bergonié","route":"/institutions/institut-bergonie/"}],"trial":[{"id":"cabone","kind":"trial","name":"CABONE","route":"/trials/cabone/"}]}}