{"entity":{"id":"archer-fusionplex","kind":"drug","name":"Archer FusionPlex panels","aka":["Archer FusionPlex","FusionPlex Pan Solid Tumor","anchored multiplex PCR fusion panel"],"tldr":"Laboratory kits that read tumour RNA to find gene fusions without needing to know the partner gene in advance; sold for research use, they are widely built into laboratories' own tests.","summary":"The panels are now sold by Integrated DNA Technologies; the pan-solid tumour version 2 targets 137 genes and the lung version 2 targets 17. IDT labels them \"For research use only. Not for use in diagnostic procedures.\" No FDA-authorised Archer device was found in the FDA databases. The method was described in 2014, when validation of a gene rearrangement panel on 319 fixed tumour samples showed 100 per cent sensitivity and specificity against reference assays (Zheng 2014). Tempus validated its own RNA test against a FusionPlex panel (Gai 2025).","status":"established","asOf":"2026-11-04","links":[{"label":"IDT: Archer FusionPlex Pan Solid Tumor v2","url":"https://www.idtdna.com/pages/products/next-generation-sequencing/archer-ngs-assay-solutions/solid-tumor-research/archer-fusionplex-pan-solid-v2-panel"}],"tags":["test","rna"],"related":["foundationone-rna","tempus-xr"],"cancers":[],"sections":[],"technologies":["rna-seq"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-zheng-anchored-multiplex-pcr-nat-med-2014"],"journals":[],"dependsOn":[],"notes":[],"brand":"FusionPlex","modality":"Targeted RNA fusion assay panels for laboratories (research use only)","mechanism":"Anchored multiplex PCR primes from one known end of a gene, so fusions are found without knowing the partner; laboratories run the panels on tumour RNA.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/archer-fusionplex/","neighbours":{"drug":[{"id":"foundationone-rna","kind":"drug","name":"FoundationOne RNA","route":"/drugs/foundationone-rna/"},{"id":"tempus-xr","kind":"drug","name":"Tempus xR","route":"/drugs/tempus-xr/"}],"technology":[{"id":"rna-seq","kind":"technology","name":"RNA sequencing & expression profiling","route":"/technologies/rna-seq/"}],"paper":[{"id":"paper-zheng-anchored-multiplex-pcr-nat-med-2014","kind":"paper","name":"Anchored multiplex PCR for targeted next-generation sequencing","route":"/key-papers/paper-zheng-anchored-multiplex-pcr-nat-med-2014/"}]}}