{"entity":{"id":"aulos-bioscience","kind":"company","name":"Aulos Bioscience","aka":[],"tldr":"Aulos Bioscience is a Californian biotech whose antibody AU-007 binds interleukin-2 so that the body's own cytokine expands cancer-killing cells without feeding the regulatory cells that dampen immunity.","summary":"Aulos Bioscience was founded by Apple Tree Partners and Biolojic Design around a computationally designed antibody, AU-007, that binds interleukin-2 at the CD25 epitope. This redirects endogenous and administered IL-2 towards CD8 T cells and natural killer cells and away from regulatory T cells. AU-007 is in phase 1/2 trials alone and with low-dose aldesleukin in solid tumours.","asOf":"2026-09-17","links":[{"label":"Official website","url":"https://www.aulosbio.com/"}],"tags":["drug-maker"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":["au-007"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo drug-maker linking round (corporate websites and regulatory records)","editedOn":"2026-09-17"},"hq":"Larkspur, California","country":"US","companyType":"biotech","website":"https://www.aulosbio.com/","founded":2020,"investors":[],"funding":[]},"route":"/companies/aulos-bioscience/","neighbours":{"drug":[{"id":"au-007","kind":"drug","name":"AU-007","route":"/drugs/au-007/"}]}}