{"entity":{"id":"bellicum","kind":"company","name":"Bellicum Pharmaceuticals","aka":["Bellicum Pharmaceuticals, Inc.","Bellicum"],"tldr":"Bellicum was a Houston cell-therapy company known for its rimiducid safety switch, which let doctors switch off infused T cells; its lead product for transplant failed to reach approval and the company wound down.","summary":"Bellicum Pharmaceuticals, founded in 2004 in Houston, built cell therapies around an inducible caspase-9 safety switch triggered by the small molecule rimiducid. Its lead product rivogenlecleucel (BPX-501), donor T cells given after haploidentical stem cell transplant in children, reached phase 3 in Europe, and later GoCAR-T products entered early trials before the company ceased operations in 2023. Its trials remain on ClinicalTrials.gov under Bellicum as lead sponsor.","asOf":"2026-09-11","links":[{"label":"Official website","url":"http://www.bellicum.com"},{"label":"ClinicalTrials.gov: trials led by Bellicum Pharmaceuticals, Inc.","url":"https://clinicaltrials.gov/search?lead=Bellicum%20Pharmaceuticals%2C%20Inc."},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q30257112"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["all-leukemia","aml"],"sections":[],"technologies":["car-t","allogeneic-hsct"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Houston, TX","country":"US","companyType":"cell-therapy","website":"http://www.bellicum.com","founded":2004,"stage":"defunct","investors":[],"funding":[]},"route":"/companies/bellicum/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"}],"technology":[{"id":"allogeneic-hsct","kind":"technology","name":"Allogeneic stem cell transplantation","route":"/technologies/allogeneic-hsct/"},{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}