{"entity":{"id":"blaze-bioscience","kind":"company","name":"Blaze Bioscience","aka":["Blaze Bioscience Inc.","Blaze Bioscience, Inc."],"tldr":"Blaze Bioscience is a Seattle company whose 'Tumor Paint', tozuleristide, is a scorpion-toxin peptide linked to a dye that lights up tumour tissue during surgery; it reached phase 3 in children's brain tumours.","summary":"Blaze Bioscience, founded in 2010 in Seattle from the work of Jim Olson at Fred Hutchinson Cancer Center, developed tozuleristide (BLZ-100), a chlorotoxin-derived peptide conjugated to the near-infrared dye indocyanine green that binds tumour cells and shows surgeons where tumour ends. It was taken into a phase 3 trial in paediatric central nervous system tumours, registered on ClinicalTrials.gov under Blaze as lead sponsor.","asOf":"2026-09-11","links":[{"label":"Official website","url":"http://www.blazebioscience.com"},{"label":"ClinicalTrials.gov: trials led by Blaze Bioscience Inc.","url":"https://clinicaltrials.gov/search?lead=Blaze%20Bioscience%20Inc."},{"label":"Wikidata","url":"https://www.wikidata.org/wiki/Q61934658"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["childhood-cancers","brain-tumours"],"sections":[],"technologies":["fluorescence-guided-surgery"],"targets":[],"drugs":[],"companies":[],"institutions":["fred-hutch"],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Seattle, WA","country":"US","companyType":"biotech","website":"http://www.blazebioscience.com","founded":2010,"stage":"private-large","investors":[],"funding":[]},"route":"/companies/blaze-bioscience/","neighbours":{"cancer":[{"id":"brain-tumours","kind":"cancer","name":"Brain and spinal cord tumours (all types)","route":"/cancers/brain-tumours/"},{"id":"childhood-cancers","kind":"cancer","name":"Childhood cancers (all types)","route":"/cancers/childhood-cancers/"}],"technology":[{"id":"fluorescence-guided-surgery","kind":"technology","name":"Fluorescence-guided surgery","route":"/technologies/fluorescence-guided-surgery/"}],"institution":[{"id":"fred-hutch","kind":"institution","name":"Fred Hutchinson Cancer Center","route":"/institutions/fred-hutch/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}