{"entity":{"id":"calm-psychotherapy","kind":"technology","name":"Managing Cancer and Living Meaningfully (CALM)","aka":["CALM therapy","CALM psychotherapy","Managing Cancer And Living Meaningfully"],"tldr":"CALM is a brief talking therapy for people with advanced cancer, designed to treat and prevent depression and distress about the end of life. In a trial of 305 people it eased depression symptoms and helped people feel more prepared.","summary":"Managing Cancer And Living Meaningfully (CALM) is a brief, manualised psychotherapeutic intervention intended to treat and prevent depression and end-of-life distress in patients with advanced cancer. In the randomised trial by Rodin and colleagues (Journal of Clinical Oncology 2018), 305 outpatients at a comprehensive cancer centre were assigned to CALM plus usual care or usual care alone. CALM participants reported less severe depressive symptoms at 3 months (the primary end point) and at 6 months, and greater end-of-life preparation at 6 months; no adverse effects were identified.","status":"established","asOf":"2026-11-04","links":[{"label":"Rodin et al., CALM randomised controlled trial (J Clin Oncol 2018)","url":"https://doi.org/10.1200/JCO.2017.77.1097"}],"tags":["supportive","psychosocial"],"related":[],"cancers":[],"sections":[],"technologies":["psycho-oncology","palliative-care"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"principle":"A brief, manualised psychotherapy for patients with advanced cancer, intended to treat and prevent depression and end-of-life distress and to address the predictable challenges these patients face.","strengths":[],"limitations":[]},"route":"/technologies/calm-psychotherapy/","neighbours":{"technology":[{"id":"palliative-care","kind":"technology","name":"Early integrated palliative care","route":"/technologies/palliative-care/"},{"id":"psycho-oncology","kind":"technology","name":"Psycho-oncology and distress screening","route":"/technologies/psycho-oncology/"}]}}